Curriculum Vitae

PD Dr. rer. nat. Felix Bock

 
 
 

Department of Ophthalmology
Experimental Ophthalmology
University of Cologne
Kerpener Strasse 62
50937 Cologne, GERMANY
Tel. (+49)-221-478 97789
Fax. (+49)-221-478 97836
Email: felix.bock@uk-koeln.de

 
 
 

Scientific career

2001-2002 Study of Biology at the University of Erlangen

2002-2004 Study of Biology at the University of Saarland, Diploma in Biology

2005-2008 PhD (summa cum laude) at the University of Erlangen

2008-2011 DFG Postdoctoral fellow at Department of Ophthalmology, University of Erlangen (Laboratory Prof. Dr. Claus Cursiefen)

2009 IZKF-foreign exchange scholarship at Schepens Eye Research Institute, Harvard Medical School, Boston, MA, USA (Laboratory Prof. Dr. Sharmila Masli)

2011- Laboratory Leader CorneaLab, Experimental Ophthalmology, Department of Ophthalmology, University of Cologne

2011- Director of the Reading Centre CORIC (Cologne Ophthalmological Reading and Image Analysis Center)

2015- Principal Investigator of Project 1 “Induction of transplant tolerance by antihem- and antilymphangiogenic therapies” in the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Department of Ophthalmology, University of Cologne

2016- Scientist in the Horizons 2020 research consortium ARREST BLINDNESS, funded by the European Union, an associated project of the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Department of Ophthalmology, University of Cologne

2016 Habilitation and Venia Legendi from the Medical Faculty of the University of Cologne (Experimental Ophthalmology). Habilitation title: Die Rolle der Lymphangiogenese bei Abstoßungsreaktionen nach Hornhaut-Transplantation/The role of lymphangiogenesis in rejection reactions after corneal transplantation

2017- Co-Principal Investigator, B3 “Novel therapeutic role of myeloid cell-derived VEGF-C and lymphangiogenesis in resolution of corneal inflammation and reestablishment of corneal transparency”, Center for Molecular Medicine Cologne (CMMC)

2018- Principal Investigator of Project P1 “Induction of corneal transplant tolerance by anti(lymph)angiogenic therapy” in the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Department of Ophthalmology, University of Cologne

 
 
 

Prizes and honors

2006 Travel Award of the “Tear Film and Ocular Surface Society” (TFOS)

2007 Young Investigator Publication Award, IZKF Erlangen

2010 Streilein Foundation Travel Grant

2009 Sicca-Research Award, DOG Ressort Dry Eye

2009 2009 ARVO ISOCB Conference Travel Grant

2011 Sicca-Research Award, DOG Ressort Dry Eye

 
 
 

Selected publications

Hou Y, Le VNH, Clahsen T, Schneider AC, Bock F, Cursiefen C (2017). Photodynamic Therapy Leads to Time-Dependent Regression of Pathologic Corneal (Lymph)Angiogenesis and Promotes High-Risk Corneal Allograft Survival. Invest Ophthalmol Vis Sci. Nov 1;58(13):5862-5869.

Bock F, Onderka J, Braun G, Schneider A-S, Hos D, Bi Y, Bachmann B, Cursiefen C (2016). Identification of novel endogenous anti(lymph)angiogenic factors in the aqueous humor. Invest Ophthalmol Vis Sci. Dec 1;57(15):6554-6560

Bock F, Matthaei M, Reinhard T, Böhringer D, Christoph J, Ganslandt T, Cursiefen C (2014). High-dose subconjunctival cyclosporine a implants do not affect corneal neovascularization after high-risk keratoplasty. Ophthalmology. Sep;121(9):1677-82.

Lipp M, Bucher F, Parthasarathy A, Hos D, Onderka J, Cursiefen C, Bock F (2014). Blockade of the VEGF isoforms in inflammatory corneal hemangiogenesis andlymphangiogenesis. Graefes Arch Clin Exp Ophthalmol. Jun;252(6):943-9.

Bucher F, Parthasarathy A, Bergua A, Onderka J, Regenfuss B, Cursiefen C, Bock F (2014). Topical Ranibizumab inhibits inflammatory corneal hem- and lymphangiogenesis. Acta Ophthalmol. Mar;92(2):143-8.

Bock F, Maruyama K, Regenfuss B, Hos D, Steven P, Heindl LM, Cursiefen C. (2013) Novel anti(lymph)angiogenic treatment strategies for corneal and ocular surface diseases. Prog Retin Eye Res. May;34:89-124.

Bucher F, Bi Y, Gehlsen U, Hos D, Cursiefen C, Bock F (2014). Regression of mature lymphatic vessels in the cornea by photodynamic therapy. Br J Ophthalmol. Mar;98(3):391-5.

Bock F, Rössner S, Onderka J, Lechmann M, Pallotta MT, Fallarino F, Boon L, Nicolette C, DeBenedette MA, Tcherepanova IY, Grohmann U, Steinkasserer A, Cursiefen C, Zinser E (2013) Topical application of soluble CD83 induces IDOmediated immune modulation, increases Foxp3+ T cells, and prolongs allogeneic corneal graft survival. J Immunol. 191(4):1965-75

Steven P*, Bock F*, Hüttmann G, Cursiefen C (2011). Intravital two-photon microscopy of immune cell dynamics in corneal lymphatic vessels. PLoS One.;6(10):e26253.

Dietrich T*, Bock F*, Yuen D, Hos D, Bachmann BO, Zahn G, Wiegand S, Chen L, Cursiefen C (2010) Cutting edge: lymphatic vessels, not blood vessels, primarily mediate immune rejections after transplantation. J Immunol 184(2):535-9 *contributed equally