Univ.-Prof. Dr. rer. nat. Thomas Langmann
Department of Ophthalmology
Experimental Immunology of the Eye
University of Cologne
Kerpener Straße 62
50937 Cologne, Germany
Tel. (+49)-221-478 7324
Fax. (+49)-221-478 84591
1990-1995 Study of Biology at the University of Regensburg, Diploma in Biology
1995-1998 PhD (magna cum laude) at the University of Regensburg
1999-2000 DFG Postdoctoral fellow at Beth Israel Hospital, Harvard Institutes of Medicine,Boston, USA (Laboratory of Prof. Dr. Daniel Tenen)
2000 – 2004 Senior Scientist, Institute for Clinical Chemistry and Laboratory Medicine at the University Hospital of Regensburg
2002 – 2005 Principal Investigator, SFB585 (Regulation of intestinal immune functions)
2004 Habilitation and Venia Legendi at the Faculty of Natural Sciencies, University of Regensburg
2004 – 2006 Privatdozent at the Institute for Clinical Chemistry and Laboratory Medicine, University Hospital of Regensburg
2006 -2010 Privatdozent and group leader at the Institute of Human Genetics, University of Regensburg
2008 – 2012 Principal Investigator, FOR1075 (Homeostasis of the retina)
2010 -2012 University Professor (W2) for Retinal Degeneration at the Institute of Human Genetics (Pro Retina foundation professorship), University of Regensburg
2012- University Professor (W3) and Chair in Experimental Immunology of the Eye, Department of Ophthalmology, University of Cologne
2014- Basic science advisor for the German Retina Society
2014- COST Action BM1302
2015- Vice-Speaker of the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Department of Ophthalmology, University of Cologne
2015- Principal Investigator of Project 6 “Role of the complement system and microglia in age-related macular degeneration” in the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Department of Ophthalmology, University of Cologne
2018- Principal Investigator of Project 6 “Role of complement receptors and microglia in age-related macular degeneration” in the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Department of Ophthalmology, University of Cologne
Prizes and honors
1994 Oskar-Karl-Forster-Stipend for young gifted students
2001 Young Investigators Award – European Atherosclerosis Society
2002 Young Investigators Award – European Lipoprotein Club
2004 Ivar-Trautschold-Prize of the German Society for Clinical Chemistry and Laboratory Medicine
2006 Research Award of the Foundation for Pathobiochemistry and Molecular Diagnostics
2009 Program Committee member European Macrophage and Dendritic Cell Society (EMDS) Meeting
2012 Novartis EYENovative Ophthalmic Research Award
2014 Visionary of the Quarter nominated by the European Vision Institute
2017 Theodor Axelfeld Prize
2018 Dr. Gaide AMD prize for excellence in research in the area of age-related macula degeneration (AMD)
Cursiefen C, Bock F, Clahsen T, Regenfuss B, Reis A, Steven P, Heindl LM, Bosch JJ, Hos D, Eming S, Grajewski R, Heiligenhaus A, Fauser S, Austin J, Langmann T. [New Therapeutic Approaches in Inflammatory Diseases of the Eye – Targeting Lymphangiogenesis and Cellular Immunity: Research Unit FOR 2240 Presents Itself]. Klin Monbl Augenheilkd. 2017 May;234(5):679-685.
Karlstetter M, Sorusch N, Caramoy A, Dannhausen K, Aslanidis K, Fauser S, Boesl MR, Nagel-Wolfrum K, Tamm ER, Jägle H, Stoehr H, Wolfrum U, Langmann T (2014) Disruption of the Retinitis Pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration. Hum Mol Genet (doi: 10.1093/hmg/ddu242 First published online: May 15, 2014).
Karlstetter M, Nothdurfter C, Aslanidis A, Moeller K, Horn F, Scholz R, Neumann H, Weber BH, Rupprecht R, Langmann T (2014) Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis. J Neuroinflammation 11:3.
Karlstetter M, Walczak Y, Weigelt K, Ebert S, Van den Brulle J, Schwer H, Fuchshofer R, Langmann T (2010) The novel activated microglia/macrophage WAP domain protein, AMWAP, acts as a counter-regulator of proinflammatory response. J Immunol 185:3379-3390.
Langmann T, Di Gioia SA, Rau I, Stohr H, Maksimovic NS, Corbo JC, Renner AB, Zrenner E, Kumaramanickavel G, Karlstetter M, Arsenijevic Y, Weber BH, Gal A, Rivolta C (2010) Nonsense mutations in FAM161A cause RP28-associated recessive retinitis pigmentosa. Am J Hum Genet 87:376-381.
Corbo JC, Lawrence KA, Karlstetter M, Myers CA, Abdelaziz M, Dirkes W, Weigelt K, Seifert M, Benes V, Fritsche LG, Weber BH, Langmann T (2010) CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors. Genome Res 20:1512-1525.