July 15, 2022
Prof. Dr. med. Sascha Fauser
Curriculum Vitae
Department of Ophthalmology
University of Cologne
Kerpener Str. 62
50937 Cologne, Germany
Email: sascha.fauser@uk-koeln.de
Scientific career
1991-1998 Studies of Medicine, University of Tübingen
1995-1996 University College London (UK), Institute of Ophthalmology (Molecular Genetics)
1998 Harvard Medical School, Boston (USA), Massachusetts Eye and Ear Infirmary, Gene Therapy
1998 Medical exam (Staatsexamen)
1998 Doctoral degree (Dr. med.) University Eye Hospital Tübingen, „summa cum laude“
1998-2002 Resident in Ophthalmology and Junior Group Leader “Gene therapy“, University Eye Hospital Tübingen
1999-2000 Visiting scientist, Medical College of Wisconsin, Milwaukee (USA)
2002-2005 Resident in Ophthalmology, University Hospital of Cologne,
2005 Board Exam in Ophthalmology (Facharzt)
2006–present Head of the Clincial Trial Center of the University Hospital of Cologne
2006-present Head of the Clinical Electrophysiology Unit
2006 Habilitation (Associate Professor) in Ophthalmology
2007-present Head physician in vitreoretinal surgery
2012- Professor of Ophthalmology (apl.), University Hospital of Cologne
2015-6 Principal Investigator of Project 6 “Role of the complement system and microglia in age-related macular degeneration” in the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Department of Ophthalmology, University of Cologne
2016- Vice-President, Roche, Basel
Prizes and honors
1998 Postdoctoral scholarship, IZKF Tübingen
1999 Hermann-Wacker-Fonds award for best doctoral thesis, German Ophthalmological Society (DOG)
2002 Postdoctoral scholarship, Center for Molecular Medicine Cologne
2003 Pharmacia, Research Award
Selected publications
Cursiefen C, Bock F, Clahsen T, Regenfuss B, Reis A, Steven P, Heindl LM, Bosch JJ, Hos D, Eming S, Grajewski R, Heiligenhaus A, Fauser S, Austin J, Langmann T. [New Therapeutic Approaches in Inflammatory Diseases of the Eye – Targeting Lymphangiogenesis and Cellular Immunity: Research Unit FOR 2240 Presents Itself]. Klin Monbl Augenheilkd. 2017 May;234(5):679-685.
Ristau T, Ersoy L, Lechanteur Y, den Hollander AI, Daha MR, Hahn M, Hoyng CB, Fauser S (2014) Allergy is a protective factor against age-related macular degeneration. Invest Ophthalmol Vis Sci. 55:210-4.
Ristau T, Paun C, Ersoy L, Hahn M, Lechanteur Y, Hoyng C, de Jong EK, Daha MR, Kirchhof B, den Hollander AI, Fauser S (2014) Impact of the common genetic associations of age-related macular degeneration upon systemic complement component C3d levels. PLoS One 9:e93459.
Helgason H, Sulem P, Duvvari MR, Luo H, Thorleifsson G, Stefansson H, Jonsdottir I, Masson G, Gudbjartsson DF, Walters GB, Magnusson OT, Kong A, Rafnar T, Kiemeney LA, Schoenmaker-Koller FE, Zhao L, Boon CJ, Song Y, Fauser S, Pei M, Ristau T, Patel S, Liakopoulos S, van de Ven JP, Hoyng CB, Ferreyra H, Duan Y, Bernstein PS, Geirsdottir A, Helgadottir G, Stefansson E, den Hollander AI, Zhang K, Jonasson F, Sigurdsson H, Thorsteinsdottir U, Stefansson K (2013) A rare nonsynonymous sequence variant in C3 is associated with high risk of age-related macular degeneration. Nat Genet. 45:1371-4.
van de Ven JP, Nilsson SC, Tan PL, Buitendijk GH, Ristau T, Mohlin FC, Nabuurs SB, Schoenmaker-Koller FE, Smailhodzic D, Campochiaro PA, Zack DJ, Duvvari MR, Bakker B, Paun CC, Boon CJ, Uitterlinden AG, Liakopoulos S, Klevering BJ, Fauser S, Daha MR, Katsanis N, Klaver CC, Blom AM, Hoyng CB, den Hollander AI (2013) A functional variant in the CFI gene confers a high risk of age-related macular degeneration. Nat Genet. 45:813-7.
Vierkotten S, Muether PS, Fauser S (2011) Overexpression of HTRA1 leads to ultrastructural changes in the elastic layer of Bruch’s membrane via cleavage of extracellular matrix components. PLoS One 6:e22959.