Publication highlights

Newest publications

Supplemental Anti Vegf A-Therapy Prevents Rebound Neovascularisation After Fine Needle Diathermy Treatment to Regress Pathological Corneal (LYMPH)Angiogenesis.
Le VNH, Hou Y, Bock F, Cursiefen C. Sci Rep. 2020 Mar 3;10(1):3908. doi: 10.1038/s41598-020-60705-z.

The TSPO-NOX1 axis controls phagocyte-triggered pathological angiogenesis in the eye. Wolf A, Herb M, Schramm M, Langmann T. Nature Communications 2020

Immune reactions after modern lamellar (DALK, DSAEK, DMEK) versus conventional penetrating corneal transplantation.
Hos D, Matthaei M, Bock F, Maruyama K, Notara M, Clahsen T, Hou Y, Le VNH, Salabarria AC, Horstmann J, Bachmann BO, Cursiefen C. Prog Retin Eye Res. 2019 Nov; Epub 2019 Jul 3

2020

Risk of Corneal Graft Rejection After High-risk Keratoplasty Following Fine-needle Vessel Coagulation of Corneal Neovascularization Combined With Bevacizumab: A Pilot Study.
Hos D, Le VNH, Hellmich M, Siebelmann S, Roters S, Bachmann BO, Cursiefen C. Transplant Direct. 2019 Apr 25, 2019 May.

Tyrosinase Is a Novel Endogenous Regulator of Developmental and Inflammatory Lymphangiogenesis.
Büttner C, Clahsen T, Regenfuss B, Dreisow ML, Steiber Z, Bock F, Reis A, Cursiefen C. Am J Pathol. 2019 Feb. Epub 2018 Nov 16.

The TSPO-NOX1 axis controls phagocyte-triggered pathological angiogenesis in the eye. Wolf A, Herb M, Schramm M, Langmann T. Nature Communications 2020.

The role of lymphocytes and phagocytes in age-related macular degeneration (AMD). Behnke V, Wolf A, Langmann T. Cell Mol Life Sci. 2020 Mar;77(5)

Microglia in Retinal Degeneration. Rashid K, Akhtar-Schaefer I, Langmann T. Front Immunol. 2019 Aug 20;10.

Anti-VEGF-A/ANG2 combotherapy limits pathological angiogenesis in the eye: a replication study. Wolf A, Langmann T. EMBO Mol Med. 2019 May

Co-inhibition of PGF and VEGF blocks their expression in mononuclear phagocytes and limits neovascularization and leakage in the murine retina.
Balser C, Wolf A, Herb M, Langmann T. J Neuroinflammation. 2019 Feb 7.

Wasmuth S, Jalilvand TV, Laffer B, Busch M, Bauer D, Langmann T, Thanos S, Kasper M, Heiligenhaus A.Phenotypic Differences in Primary Murine Microglia Treated with NOD1, NOD2, and NOD1/2 Agonists. J Mol Neurosci. 2020 Apr;70(4):600-609.

Schrittenlocher S, Schlereth SL, Siebelmann S, Hayashi T, Matthaei M, Bachmann B, Cursiefen C.Long-term outcome of descemet membrane endothelial keratoplasty (DMEK) following failed penetrating keratoplasty (PK). Acta Ophthalmol. 2020 Mar 20.

Hayashi T, Hos D, Schrittenlocher S, Siebelmann S, Matthaei M, Franklin J, Clahsen T, Bock F, Bachmann B, Cursiefen C.Effect of Iris Color on the Outcome of Descemet Membrane Endothelial Keratoplasty. Cornea. 2020 Mar 13.

Le VNH, Wabnig F, Bachmann B, Cursiefen C.Epithelial downgrowth after Descemet membrane endothelial keratoplasty. Eur J Ophthalmol. 2020 Mar 12:1120672120912413.

Kasper M, Walscheid K, Laffer B, Bauer D, Busch M, Loser K, Vogl T, Langmann T, Ganser G, Rath T, Heiligenhaus A.Phenotype of Innate Immune Cells in Uveitis Associated with Axial Spondyloarthritis- and Juvenile Idiopathic Arthritis-associated Uveitis. Ocul Immunol Inflamm. 2020 Mar 11:1-10.

Gietzelt C, von Goscinski C, Lemke J, Schaub F, Hermann MM, Dietlein TS, Cursiefen C, Heindl LM, Enders P.Dynamics of structural reversal in Bruch’s membrane opening-based morphometrics after glaucoma drainage device surgery. Graefes Arch Clin Exp Ophthalmol. 2020 Mar 5.

Le VNH, Hou Y, Bock F, Cursiefen C.Supplemental Anti Vegf A-Therapy Prevents Rebound Neovascularisation After Fine Needle Diathermy Treatment to Regress Pathological Corneal (LYMPH)Angiogenesis. Sci Rep. 2020 Mar 3;10(1):3908.

Schaub F, Collmer M, Schrittenlocher S, Bachmann BO, Cursiefen C, Hos D.Outcome of Descemet Membrane Endothelial Keratoplasty Using Corneas from Donors ≥80 Years of Age. Am J Ophthalmol. 2020 Mar;211:200-206.

Behnke V, Wolf A, Langmann T.The role of lymphocytes and phagocytes in age-related macular degeneration (AMD). Cell Mol Life Sci. 2020 Mar;77(5):781-788.

Mor JM, Schultheis A, Heindl LM, Bornfeld N, Hermann M, Cursiefen C.Excision and tectonic covering of a vascular leiomyoma of the ciliary body with large anterior staphyloma using scleral patch graft]. Ophthalmologe. 2020 Mar;117(3):270-276.

Guo Y, Schaub F, Mor JM, Jia R, Koch KR, Heindl LM.A Simple Standardized Three-Dimensional Anthropometry for the Periocular Region in a European Population. Plast Reconstr Surg. 2020 Mar;145(3):514e-523e.

Atta G, Tempfer H, Kaser-Eichberger A, Guo Y, Schroedl F, Traweger A, Heindl LM.The lymphangiogenic and hemangiogenic privilege of the human sclera. Ann Anat. 2020 Feb 28;230:151485.

Pinto-Fraga J, Calonge M, Enríquez-de-Salamanca A, Fernández I, González-García MJ, Steven P.Development of a Questionnaire for Detecting Changes in Dry Eye Disease-Related Symptoms. Eye Contact Lens. 2020 Feb 24.

Steven P, Faust C, Holtick U, Scheid C, Tahmaz V, Stern ME, Gehlsen U.Adverse environmental conditions are a risk factor for ocular GvHD after allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant. 2020 Feb 10.

Clahsen T, Büttner C, Hatami N, Reis A, Cursiefen C.Role of Endogenous Regulators of Hem- And Lymphangiogenesis in Corneal Transplantation. J Clin Med. 2020 Feb 9;9(2).

Schaub F, Gözlügöl N, von Goscinski C, Enders P, Heindl LM, Dahlke C.Outcome of autologous platelet concentrate and gas tamponade compared to heavy silicone oil tamponade in persistent macular hole surgery. Eur J Ophthalmol. 2020 Feb.

Heinen H, Notara M, Loreck N, Grajewski RS, Cursiefen C. [Unclear bilateral perilimbal swelling]. Ophthalmologe. 2020 Feb 3.

Heindl LM [Periocular basal cell carcinoma]. Ophthalmologe. 2020 Feb;117(2):93-94..

Kakkassery V, Heindl LM. [Standard operation procedure in periorbital basal cell carcinoma]. Ophthalmologe. 2020 Feb;117(2):124.

Kakkassery V, Emmert S, Adamietz IA, Kovács G, Jünemann AM, Otte C, Zimbelmann M, Brosig A, Grisanti S, Heindl LM. [Alternative treatment options for periorbital basal cell carcinoma]. Ophthalmologe. 2020 Feb;117(2):113-123.

. Rokohl AC, Kopecky A, Guo Y, Kakkassery V, Mor JM, Loreck N, Koch KR, Heindl LM. [Surgical resection with ophthalmoplastic reconstruction : Gold standard in periocular basal cell carcinoma]. Ophthalmologe. 2020 Feb;117(2):95-105

Boeckmann L, Martens MC, Kakkassery V, Heindl LM, Emmert S. [Molecular genetic investigations as the basis for targeted treatment of basal cell carcinoma of the eye]. Ophthalmologe. 2020 Feb;117(2):106-112.

Loreck N, Adler W, Siebelmann S, Rokohl AC, Heindl LM, Cursiefen C, Bachmann BO, Matthaei M.Morning myopic shift and glare in advanced Fuchs endothelial corneal dystrophy. Am J Ophthalmol. 2020 Jan 16. pii:

Rokohl AC, Koch KR, Mor JM, Loreck N, Schlaak M, Mauch C, Bechrakis NE, Mohi A, Kakkassery V, Heindl LM. [Personalized medicine in the treatment of periocular tumors : Targeted treatment and use of immune checkpoint inhibitors]. Ophthalmologe. 2020 Jan 14.

Grajewski RS, Boelke AC, Adler W, Pape A, Schroedl F, Hueber A, Albus C, Vitinius F, Heindl LM Perceived Stress Levels in Adult Patients With Uveitis. Front Psychiatry. 2020 Jan 8;10:916.

Rokohl AC, Guo Y, Mor JM, Loreck N, Koch KR, Heindl LM. [Intubation Systems in Lacrimal Drainage Surgery – a Current Overview]. Klin Monbl Augenheilkd. 2020 Jan;237(1):20-28.

Eberwein P, Krösser S, Steven P.Semifluorinated Alkane Eye Drops in Chronic Ocular Graft-versus-Host Disease: A Prospective, Multicenter, Noninterventional Study. Ophthalmic Res. 2020;63(1):50-58

Rokohl AC, Löser H, Mor JM, Loreck N, Koch KR, Heindl LM. [Young male patient with unusual space-occupying lesion of the lower eyelid]. Ophthalmologe. 2020 Jan;117(1):73-77.

Panzer S, Pernter P, Heindl LM Zink AR. Reply. Ophthalmology. 2020 Jan;127(1):e5.

2019

Enders P, Adler W, Kiessling D, Weber V, Schaub F, Hermann MM, Dietlein T, Cursiefen C, Heindl LM Evaluation of two-dimensional Bruch’s membrane opening minimum rim area for glaucoma diagnostics in a large patient cohort. Acta Ophthalmol. 2019;97(1): 60-67

Kersten E, Sitnilska V, Altay L, Schick T, Enders P, de Jong EK, Langmann T, den Hollander AI, Fauser S, Hoyng CB Risk factors for progression from early and intermediate to late age-related macular degeneration: 5-year follow-up in the EUGENDA cohort
Acta Ophthalmol. 2019;97 262: 12-12

Schrittenlocher S, Bachmann B, Cursiefen C Impact of donor tissue diameter on postoperative central endothelial cell density in Descemet Membrane Endothelial Keratoplasty. Acta Ophthalmol. 2019;97(4): e618-e622

Akhtar-Schaefer I, Reuten R, Koch M, Pietsch M, Langmann T AMD-Associated HTRA1 Variants Do Not Influence TGF-? Signaling in Microglia.
Adv Exp Med Biol. 2019;1185: 3-

Volz C, Mirza M, Langmann T, Jägle H ERG Alteration Due to the rd8 Mutation of the Crb1 Gene in Cln3 Mice. Adv Exp Med Biol. 2019;1185: 395-400

Enders P, Hall J, Bornhauser M, Mansouri K, Altay L, Schrader S, Dietlein TS, Bachmann BO, Neuhann T, Cursiefen C Telemetric Intraocular Pressure Monitoring after Boston Keratoprosthesis Surgery Using the Eyemate-IO Sensor: Dynamics in the First Year. Am J Ophthalmol. 2019;206: 256-263

Schaub F, Gerber F, Adler W, Enders P, Schrittenlocher S, Heindl LM, Cursiefen C, Bachmann BO Corneal Densitometry as a Predictive Diagnostic Tool for Visual Acuity Results After Descemet Membrane Endothelial Keratoplasty. Am J Ophthalmol. 2019;198: 124-129

Büttner C, Clahsen T, Regenfuss B, Dreisow ML, Steiber Z, Bock F, Reis A, Cursiefen C Tyrosinase Is a Novel Endogenous Regulator of Developmental and Inflammatory Lymphangiogenesis. Am J Pathol. 2019;189(2): 440-448

Salabarria AC, Braun G, Heykants M, Koch M, Reuten R, Mahabir E, Cursiefen C, Bock F Local VEGF-A blockade modulates the microenvironment of the corneal graft bed.
Am J Transplant. 2019;19(9): 2446-2456 (Impact(2017)=6.493, Typ=Article; Journal Article)

Matthaei M, Hribek A, Clahsen T, Bachmann B, Cursiefen C, Jun AS Fuchs Endothelial Corneal Dystrophy: Clinical, Genetic, Pathophysiologic, and Therapeutic Aspects. Annu Rev Vis Sci. 2019;5: 151-175

Hos D, Schaub F, Cursiefen C Does anterior chamber-associated immune deviation (ACAID) play a role in posterior lamellar keratoplasty? Case report of a splenectomized patient. BMC Ophthalmol. 2019;19(1): 100

Hung Le VN, Bachmann B, Avgitidou G, Cursiefen C Treatment of corneal edema secondary to chemical burn by Descemet membrane endothelial keratoplasty (DMEK). Can J Ophthalmol. 2019;54(1): e43-e47

Enders P, Avgitidou G, Heindl LM, Dietlein TS, Cursiefen C Temporary Filtering Bleb Failure Induced by Anterior Chamber Sulfur Hexafluoride Gas: A Complication after Descemet Membrane Endothelial Keratoplasty Case Rep Ophthalmol. 2019;10(1): 120-126

Matthaei M, Leitl C, Cursiefen C, Heindl LM Correlation of extracellular matrix-related gene expression with objective Fuchs endothelial corneal dystrophy severity. Clin Experiment Ophthalmol. 2019;47(5): 671-673

Mor JM, Rokohl AC, Koch KR, Heindl LM Sentinel lymph node biopsy in the management of conjunctival melanoma: current insights. Clin Ophthalmol. 2019;13: 1297-1302

Bachmann B, Händel A, Siebelmann S, Matthaei M, Cursiefen C Mini-Descemet Membrane Endothelial Keratoplasty for the Early Treatment of Acute Corneal Hydrops in Keratoconus. Cornea. 2019;38(8): 1043-1048

Behaegel J, Zakaria N, Tassignon MJ, Leysen I, Bock F, Koppen C, Ní Dhubhghaill S Short- and Long-Term Results of Xenogeneic-Free Cultivated Autologous and Allogeneic Limbal Epithelial Stem Cell Transplantations. Cornea. 2019;38(12): 1543-1549

Siebelmann S, Händel A, Matthaei M, Bachmann B, Cursiefen C Microscope-Integrated Optical Coherence Tomography-Guided Drainage of Acute Corneal Hydrops in Keratoconus Combined With Suturing and Gas-Aided Reattachment of Descemet Membrane. Cornea. 2019;38(8): 1058-1061

Siggel R, Christofi E, Giasoumi F, Adler W, Siebelmann S, Bachmann B, Cursiefen C, Heindl LM Changes in Corneal Biomechanical Properties After Descemet Membrane Endothelial Keratoplasty. Cornea. 2019;38(8): 964-969

Schlereth SL, Karlstetter M, Hos D, Matthaei M, Cursiefen C, Heindl LM Detection of Pro- and Antiangiogenic Factors in the Human Sclera. Curr Eye Res. 2019;44(2): 172-184

Wolf A, Langmann T Anti-VEGF-A/ANG2 combotherapy limits pathological angiogenesis in the eye: a replication study. EMBO Mol Med. 2019;11(5)

Klee K, Storti F, Barben M, Samardzija M, Langmann T, Dunaief J, Grimm C Systemic knockout of Tspo in mice does not affect retinal morphology, function and susceptibility to degeneration. Exp Eye Res. 2019;188: 107816

Yu X, He X, Heindl LM, Song X, Fan J, Jia R KIF15 plays a role in promoting the tumorigenicity of melanoma.
Exp Eye Res. 2019;185: 107598

Xu Y, Wang H, Li F, Heindl LM, He X, Yu J, Yang J, Ge S, Ruan J, Jia R, Fan X Long Non-coding RNA LINC-PINT Suppresses Cell Proliferation and Migration of Melanoma via Recruiting EZH2. Front Cell Dev Biol. 2019;7: 350

Laffer B, Bauer D, Wasmuth S, Busch M, Jalilvand TV, Thanos S, Meyer Zu Hörste G, Loser K, Langmann T, Heiligenhaus A, Kasper M Loss of IL-10 Promotes Differentiation of Microglia to a M1 Phenotype.
Front Cell Neurosci. 2019;13: 430

Rashid K, Akhtar-Schaefer I, Langmann T Microglia in Retinal Degeneration. Front Immunol. 2019;10: 1975

Willrodt AH, Salabarria AC, Schineis P, Ignatova D, Hunter MC, Vranova M, Golding-Ochsenbein AM, Sigmund E, Romagna A, Strassberger V, Fabbi M, Ferrini S, Cursiefen C, Neri D, Guenova E, Bock F, Halin C ALCAM Mediates DC Migration Through Afferent Lymphatics and Promotes Allospecific Immune Reactions. Front Immunol. 2019;10: 759

Van Schil K, Naessens S, Van de Sompele S, Carron M, Aslanidis A, Van Cauwenbergh C, Mayer AK, Van Heetvelde M, Bauwens M, Verdin H, Coppieters F, Greenberg ME, Yang MG, Karlstetter M, Langmann T, De Preter K, Kohl S, Cherry TJ, Leroy BP, CNV Study Group , De Baere E, Lupski JR, Carvalho C, van Min M, Klous P, De Jaegere S, Hooghe S Correction: Mapping the genomic landscape of inherited retinal disease genes prioritizes genes prone to coding and noncoding copy-number variations.
Genet Med. 2019;21(8): 1998

Khan AS, Langmann T Aryl hydrocarbon receptor ligands for the modulation of retinal microglia homeostasis Glia. 2019;67 S1: E626-E627

Taiwo MT, Langmann T The role of Platelet Derived Growth Factors in microglia mediated responses: implications for retina degenerative diseases. Glia. 2019;67 S1: E534-E535

Guo Y, Rokohl AC, Schaub F, Hou X, Liu J, Ruan Y, Jia R, Koch KR, Heindl LM Reliability of periocular anthropometry using three-dimensional digital stereophotogrammetry. Graefes Arch Clin Exp Ophthalmol. 2019;257(11): 2517-2531

Guo Y, Koch KR, Heindl LM Transcaruncular laser-assisted StopLoss Lester Jones tube surgery for lacrimal canalicular obstructions. Graefes Arch Clin Exp Ophthalmol. 2019;257(7): 1569-1570

Heindl LM, Augustin AJ, Messmer EM, ADVISE study group , Bayerl-Löhe K, Böhringer D, Goos D, Herb S, Koch KR, Koinzer S, Lanzl IM, Lorenz K, Rist K, Reinhard T, Scheer-Baumann H ADenoVirus Initiative Study in Epidemiology (ADVISE)-results of a multicenter epidemiology study in Germany. Graefes Arch Clin Exp Ophthalmol. 2019;257(1): 249-251

Kiessling D, Christ H, Gietzelt C, Schaub F, Dietlein TS, Cursiefen C, Heindl LM, Enders P Impact of ab-interno trabeculectomy on Bruch’s membrane opening-based morphometry of the optic nerve head for glaucoma progression analysis. Graefes Arch Clin Exp Ophthalmol. 2019;257(2): 339-347

Loeser J, Schwemmer J, Gostian AO, Gostian M, Bachmann B, Cursiefen C, Heindl LM Postoperative pain following Descemet membrane endothelial keratoplasty (DMEK): a prospective study. Graefes Arch Clin Exp Ophthalmol. 2019;257(10): 2203-2211

Rokohl AC, Adler W, Koch KR, Mor JM, Jia R, Trester M, Pine NS, Pine KR, Heindl LM Cryolite glass prosthetic eyes-the response of the anophthalmic socket. Graefes Arch Clin Exp Ophthalmol. 2019;257(9): 2015-2023

Rokohl AC, Trester M, Pine KR, Heindl LM Risk of breakage of cryolite glass prosthetic eyes.
Graefes Arch Clin Exp Ophthalmol. 2019;257(2): 437-438

Schaub F, Bachmann BO, Cursiefen C, Hos D Midterm follow-up of immune reactions after Descemet membrane endothelial keratoplasty (DMEK). Graefes Arch Clin Exp Ophthalmol. 2019;257(8): 1811-1812

Schrittenlocher S, Bachmann B, Tiurbe AM, Tuac O, Velten K, Schmidt D, Cursiefen C Impact of preoperative visual acuity on Descemet Membrane Endothelial Keratoplasty (DMEK) outcome. Graefes Arch Clin Exp Ophthalmol. 2019;257(2): 321-329)

Rokohl AC, Koch KR, Kabbasch C, Kreppel M, Lüers JC, Grau S, Heindl LM [Importance of interdisciplinary collaboration for optimal treatment of orbital tumors]. HNO. 2019;67(7): 528-533

Osae EA, Steven P, Redfern R, Hanlon S, Smith CW, Rumbaut RE, Burns AR Dyslipidemia and Meibomian Gland Dysfunction: Utility of Lipidomics and Experimental Prospects with a Diet-Induced Obesity Mouse Model. Int J Mol Sci. 2019;20(14)

Bachmann B, Handel A, Siebelmann SE, Matthaei M, Cursiefen C Descemet Membrane Endothelial Keratoplasty with small grafts (mini-DMEK) for the treatment of focal defects in Descemet’s membrane Invest Ophthalmol Vis Sci. 2019;60(9

Bock F, Schneider AC, Cursiefen C, Koch M, Reuten R, Mahabir E, Braun G, Heykants M Local VEGF-A blockade modulates the microenvironment of corneal transplantion side Invest Ophthalmol Vis Sci. 2019;60(9

Clahsen T, Buttner C, Regenfuss B, Gabriel T, Bock F, Reis A, Cursiefen C Tyrosinase is a novel endogenous inhibitor of lymphangiogenesis Invest Ophthalmol Vis Sci. 2019;60(9):

Cursiefen C, Bachmann B, Hos D Preoperative Reduction of Corneal Neovascularization by Fine-Needle Vessel Coagulation Combined with Bevacizumab Decreases the Risk of Graft Rejection after Subsequent High-Risk Keratoplasty: a clinical pilot study Invest Ophthalmol Vis Sci. 2019;60(9):

Enders P, Hall J, Bornhauser M, Mansouri K, Altay L, Schrader S, Dietlein TS, Bachmann B, Neuhann T, Cursiefen C Telemetric Intraocular Pressure Monitoring in Boston Keratoprosthesis Patients with the Eyemate-IO Pressure Sensor: Dynamics in the first year of follow-up Invest Ophthalmol Vis Sci. 2019;60(9)

Gehlsen U, Faust C, Hess D, Siebelmann SE, Stern ME, Holtick U, Scheid C, Steven P Are Adverse Environmental Conditions during Allogeneic Hematopoietic Stem Cell Transplantation a Risk Factor for Ocular Graft-versus-Host Disease? Invest Ophthalmol Vis Sci. 2019;60(9):

Gietzelt C, von Goscinski C, Lemke J, Schaub F, Hermann MM, Dietlein TS, Cursiefen C, Heindl LM, Enders P Dynamics of structural reversal in Bruch’s membrane opening based parameters to assess neuroretinal rim after glaucoma drainage device implantation Invest Ophthalmol Vis Sci. 2019;60(9

Handel A, Siebelmann SE, Wabnig F, Ilmarinen T, Budko B, Koivusalo L, Skottman H, Cursiefen C, Bachmann B Systemic Immunosuppression with Tacrolimus loaded osmotic pumps in a Rabbit Model for Limbal Stem Cell Transplantation Invest Ophthalmol Vis Sci. 2019;60(9):

Hoerster R, von Netzer C, Schulze L, Obstmayer J, Tahmaz E, Heindl LM Glaucoma as a risk factor for early pseudophakic macular edema – an analysis of 1000 cataract surgeries Invest Ophthalmol Vis Sci. 2019;60(9):

Hos D, Kiesewetter A, Cursiefen C, Eming SA CSFR-1(+) CX3CR1(+) resident corneal macrophages regulate inflammatory corneal Invest Ophthalmol Vis Sci. 2019;60(9

Hou YH, Le VNH, Bock F, Cursiefen C Comparison of UV-light crosslinking and Fine needle-diathermy to regress pathological corneal lymphatic and blood vessels in vivo Invest Ophthalmol Vis Sci. 2019;60(9

Hribek A, Clahsen T, Siebelmann SE, Heindl LM, Bachmann B, Cursiefen C, Matthaei M A model of Fuchs Endothelial Corneal Dystrophy – related extracellular matrix expression by miR-29 knockdown in vitro Invest Ophthalmol Vis Sci. 2019;60(9

Kasper M, Walscheid K, Laffer B, Bauer D, Busch M, Loser K, Vogl T, Langmann T, Ganser G, Rath T, Heiligenhaus A Phenotype of innate immune cells in uveitis associated with axial spondyloarthritis-versus juvenile idiopathic arthritis-associated uveitis Invest Ophthalmol Vis Sci. 2019;60(9):

Le VNH, Hou Y, Witt M, Bock F, Cursiefen C Vegf Trapr1r2 Suspended In Semifluorinated Alkanes Inhibits Inflammatory Corneal Hem- And Lymphangiogenesis Invest Ophthalmol Vis Sci. 2019;60(9): –

Matthaei M, Schmidt M, Hribek A, Siebelmann SE, Bachmann B, Cursiefen C, Heindl LM Localization of CDKN2A/p16-positive cells in the corneal endothelium of Fuchs dystrophy patients Invest Ophthalmol Vis Sci. 2019;60(9):

Notara M, Behoudifard S, Schumacher B, Cursiefen C UV light-blocking contact lenses prevent UVB-induced DNA and oxidative damage of the limbal stem cell niche, protect against inflammation and maintain putative stem cell phenotype Invest Ophthalmol Vis Sci. 2019;60(9):

Steven P, Hess D, Jens H, Dautzenberg FM, Stern ME, Gehlsen U Application of a Cannabinoid-Receptor Agonist in a Mouse Model of Desiccating Stress Invest Ophthalmol Vis Sci. 2019;60(9):

Volz C, Mirza M, Langmann T, Jaegle H Extended electrophysiological characterization of the retinal degeneration in CLN6nclf mice Invest Ophthalmol Vis Sci. 2019;60(9

Notara M, Lentzsch A, Clahsen T, Behboudifard S, Braun G, Cursiefen C Bevacizumab Induces Upregulation of Keratin 3 and VEGFA in Human Limbal Epithelial Cells in Vitro. J Clin Med. 2019;8(11)

Lang BM, Balermpas P, Bauer A, Blum A, Brölsch GF, Dirschka T, Follmann M, Frank J, Frerich B, Fritz K, Hauschild A, Heindl LM, Howaldt HP, Ihrler S, Kakkassery V, Klumpp B, Krause-Bergmann A, Löser C, Meissner M, Sachse MM, Schlaak M, Schön MP, Tischendorf L, Tronnier M, Vordermark D, Welzel J, Weichenthal M, Wiegand S, Kaufmann R, Grabbe S S2k-Leitlinie Basalzellkarzinom der Haut – Teil 1: Epidemiologie, Genetik und Diagnostik. J Dtsch Dermatol Ges. 2019;17(1): 94-104

Balser C, Wolf A, Herb M, Langmann T Co-inhibition of PGF and VEGF blocks their expression in mononuclear phagocytes and limits neovascularization and leakage in the murine retina. J Neuroinflammation. 2019;16(1): 26

Hos D, Cursiefen C, Dahlke C Von Hippel Lindau Disease. J Pediatr. 2019;209: 252

Rokohl AC, Trester M, Mor JM, Loreck N, Koch KR, Heindl LM Customizing a Cryolite Glass Prosthetic Eye. J Vis Exp. 2019;(152

Bachmann BO, Pleyer U, Maier PC, Reinhard T, Seitz B, Cursiefen C [Perioperative/Postoperative Anti-Inflammatory Therapy During/After Corneal Surgery/Transplantation]. Klin Monatsbl Augenheilkd. 2019;236(5): 653-661

Cursiefen C, Heiligenhaus A [Standardisation of Perioperative Antiinflammatory Therapy].
Klin Monatsbl Augenheilkd. 2019;236(5): 634-635

Rokohl AC, Mor JM, Trester M, Koch KR, Heindl LM [Rehabilitation of Anophthalmic Patients with Prosthetic Eyes in Germany Today – Supply Possibilities, Daily Use, Complications and Psychological Aspects]. Klin Monatsbl Augenheilkd. 2019;236(1): 54-62

Cursiefen C, Cordeiro F, Cunha-Vaz J, Wheeler-Schilling T, Scholl HPN, EVI Steering Board Unmet Needs in Ophthalmology: A European Vision Institute-Consensus Roadmap 2019-2025. Ophthalmic Res. 2019;62(3): 123-133

Bachmann B, Schrittenlocher S, Matthaei M, Siebelmann S, Cursiefen C [Descemet membrane endothelial keratoplasty in complex eyes]. Ophthalmologe. 2019;116(3): 228-235

Cursiefen C [Kein Titel angegeben] Ophthalmologe. 2019;116(11): 1006-1007

Cursiefen C, Cordeiro F, Cunha-Vaz J, Wheeler-Schilling T, Scholl HPN, das EVI Steering Board , Boon C, Fauser S, Sivaprasad S, Luthert P, Sahel J, Zrenner E [Unmet research and developmental needs in ophthalmology : A consensus-based road map of the European Vision Institute for 2019-2025].
Ophthalmologe. 2019;116(9): 838-849

Cursiefen C, Bachmann B [Treatment of Fuchs’ endothelial dystrophy with DMEK : Experiences from the past 10 years]. Ophthalmologe. 2019;116(3): 218-220

Cursiefen C [Ophthalmology: our discipline with a future].
Ophthalmologe. 2019;116(9): 815-816 (Impact(2017)=0.842, Typ=Editorial Material; Editorial)

Gietzelt C, Blau T, Koch KR, Grau S, Heindl LM [Swelling in the region of the eyebrow in a 21-year-old female patient]. Ophthalmologe. 2019;116(8): 794-796

Heindl LM [Current concepts in diagnosis and treatment of iris tumors].
Ophthalmologe. 2019;116(4): 310-312

Kakkassery V, Jünemann AM, Scheef BO, Grisanti S, Heindl LM [New molecular pathological strategies for malignant iris tumors]. Ophthalmologe. 2019;116(4): 324-331

Koch KR, Mor JM, Avgitidou G, Kakkassery V, Rokohl AC, Heindl LM [Clinico-echographic diagnostics of iris tumors]. Ophthalmologe. 2019;116(4): 313-323

Kopecky A, Koch KR, Schroedl F, Rokohl AC, Nemcansky J, Heindl LM [Cheek-midface lift for revision following failed excessive lower eyelid blepharoplasty]. Ophthalmologe. 2019;116(5): 472-476

Lauterbach B, Kakkassery V, Debus D, Heindl LM, Schultz ES [Advanced periocular basal cell carcinoma-a therapeutic challenge]. Ophthalmologe. 2019;116(3): 273-277

Matthaei M, Schrittenlocher S, Hos D, Siebelmann S, Bucher F, Schaub F, Hoerster R, Siggel R, Roters S, Heindl LM, Bachmann B, Cursiefen C [10 years of Descemet membrane endothelial keratoplasty in Fuchs endothelial corneal dystrophy : What have we learned?] Ophthalmologe. 2019;116(3): 236-242

Matthaei M, Bachmann B, Hos D, Siebelmann S, Schaub F, Cursiefen C [Boston type I keratoprosthesis implantation technique : Video article]. Ophthalmologe. 2019;116(1): 67-72

Mor JM, Koch KR, Kakkassery V, Cursiefen C, Heindl LM [New treatment options for iridociliary tumors].
Ophthalmologe. 2019;116(4): 332-339

Müller J, Schiffer A, Cursiefen C, Heindl LM [Diversity in daily clinical practice of ophthalmology].
Ophthalmologe. 2019;

Rokohl AC, Ortmann M, Mor JM, Koch KR, Heindl LM [Slowly progressive upper eyelid swelling and ptosis].
Ophthalmologe. 2019;116(4): 387-390

Enders P, Hall J, Bornhauser M, Mansouri K, Altay L, Schrader S, Dietlein TS, Bachmann BO, Neuhann T, Cursiefen C Telemetric Intraocular Pressure Monitoring after Boston Keratoprosthesis Surgery. Ophthalmology. 2019;126(2): 322-324

Heindl LM, Pernter P, Zink AR, Panzer S The Eyes of Oetzi: The Tyrolean Iceman Mummy. Ophthalmology. 2019;126(4): 530

Wirta DL, Torkildsen GL, Moreira HR, Lonsdale JD, Ciolino JB, Jentsch G, Beckert M, Ousler GW, Steven P, Krösser S A Clinical Phase II Study to Assess Efficacy, Safety, and Tolerability of Waterfree Cyclosporine Formulation for Treatment of Dry Eye Disease. Ophthalmology. 2019;126(6): 792-800

Hos D, Matthaei M, Bock F, Maruyama K, Notara M, Clahsen T, Hou Y, Le VNH, Salabarria AC, Horstmann J, Bachmann BO, Cursiefen C Immune reactions after modern lamellar (DALK, DSAEK, DMEK) versus conventional penetrating corneal transplantation. Prog Retin Eye Res. 2019;73: 100768

Enders P, Heindl LM, Fauser S Correspondence. Retina. 2019;39(11): e47

Hintzen L, Karow U, Khan A, Kr?nke M, Langmann T, Uterm?hlen O How do microglia cells respond to Zika virus infection? Scand J Immunol. 2019;90(6):

Kiesewetter A, Cursiefen C, Eming SA, Hos D Phase-specific functions of macrophages determine injury-mediated corneal hem- and lymphangiogenesis. Sci Rep. 2019;9(1): 308

Hos D, Le VNH, Hellmich M, Siebelmann S, Roters S, Bachmann BO, Cursiefen C Risk of Corneal Graft Rejection After High-risk Keratoplasty Following Fine-needle Vessel Coagulation of Corneal Neovascularization Combined With Bevacizumab: A Pilot Study. Transplant Direct. 2019;5(5): e452

2018

Akhtar-Schafer I, Wang L, Krohne TU, Xu H, Langmann T (2018) Modulation of three key innate immune pathways for the most common retinal degenerative diseases. EMBO molecular medicine 10

Notara M, Lentzsch A, Coroneo M, Cursiefen C (2018) The Role of Limbal Epithelial Stem Cells in Regulating Corneal (Lymph)angiogenic Privilege and the Micromilieu of the Limbal Niche following UV Exposure. Stem cells international 2018: 8620172

Le VNH, Hou Y, Horstmann J, Bock F, Cursiefen C (2018) Novel Method to Detect Corneal Lymphatic Vessels In Vivo by Intrastromal Injection of Fluorescein. Cornea 37: 267-271

Langmann T The role of the microglia in age-related macular degeneration
Acta Ophthalmol. 2018;96 261: 138-139

Nobacht S, Bachman B, Domanian A, Hos D, Matthaei M Radboud/Cologne Fuchs Endothelial Dystrophy Scale (Radboud/Cologne FECD Scale): a prospective study Acta Ophthalmol. 2018;96 S260: 6-6

Volz C, Mirza M, Langmann T, Jägle H Further Characterization of the Predominant Inner Retinal Degeneration of Aging Cln3 Knock-In Mice. Adv Exp Med Biol. 2018;1074: 403-411

Flockerzi E, Maier P, Böhringer D, Reinshagen H, Kruse F, Cursiefen C, Reinhard T, Geerling G, Torun N, Seitz B, all German Keratoplasty Registry Contributors Trends in Corneal Transplantation from 2001 to 2016 in Germany: A Report of the DOG-Section Cornea and its Keratoplasty Registry. Am J Ophthalmol. 2018;188: 91-98

Gietzelt C, Lemke J, Schaub F, Hermann MM, Dietlein TS, Cursiefen C, Enders P, Heindl LM Structural Reversal of Disc Cupping After Trabeculectomy Alters Bruch Membrane Opening-Based Parameters to Assess Neuroretinal Rim. Am J Ophthalmol. 2018;194: 143-152

Schrittenlocher S, Schaub F, Hos D, Siebelmann S, Cursiefen C, Bachmann B Evolution of Consecutive Descemet Membrane Endothelial Keratoplasty Outcomes Throughout a 5-Year Period Performed by Two Experienced Surgeons.
Am J Ophthalmol. 2018;190: 171-178

Siebelmann S, Ramos SL, Matthaei M, Scholz P, Schrittenlocher S, Heindl LM, Bachmann B, Cursiefen C Factors Associated With Early Graft Detachment in Primary Descemet Membrane Endothelial Keratoplasty. Am J Ophthalmol. 2018;192: 249-250

Hou Y, Le VNH, Tóth G, Siebelmann S, Horstmann J, Gabriel T, Bock F, Cursiefen C UV light crosslinking regresses mature corneal blood and lymphatic vessels and promotes subsequent high-risk corneal transplant survival. Am J Transplant. 2018;18(12): 2873-2884

Kopecky A, Rokohl AC, Heindl LM Reconstruction Techniques of posterior Eyelid Lamella Augenheilkund Up2date. 2018;8(4): 287-298

Osae EA, Ablorddepey RK, Horstmann J, Kumah DB, Steven P Assessment of meibomian glands using a custom-made meibographer in dry eye patients in Ghana. BMC Ophthalmol. 2018;18(1):

Wiedemann J, Rashid K, Langmann T Resveratrol induces dynamic changes to the microglia transcriptome, inhibiting inflammatory pathways and protecting against microglia-mediated photoreceptor apoptosis. Biochem Biophys Res Commun. 2018;501(1): 239-245

Rashid K, Geissl L, Wolf A, Karlstetter M, Langmann Transcriptional regulation of Translocator protein (18 kDa) (TSPO) in microglia requires Pu.1, Ap1 and Sp factors. Biochim Biophys Acta Gene Regul Mech. 2018;1861(12): 1119-1133 T

Tempfer H, Kaser-Eichberger A, Lehner C, Gehwolf R, Korntner S, Kunkel N, Wagner A, Gruetz M, Heindl LM, Schroedl F, Traweger A Bevacizumab Improves Achilles Tendon Repair in a Rat Model. Cell Physiol Biochem. 2018;46(3): 1148-1158

Le VNH, Bock F, Cursiefen C Cornea. 2018;37(4): e23-e24

Le VNH, Hou Y, Horstmann J, Bock F, Cursiefen C Novel Method to Detect Corneal Lymphatic Vessels In Vivo by Intrastromal Injection of Fluorescein. Cornea. 2018;37(2): 267-271

Siebelmann S, Lopez Ramos S, Scholz P, Matthaei M, Schrittenlocher S, Heindl LM, Bachmann B, Cursiefen C Graft Detachment Pattern After Descemet Membrane Endothelial Keratoplasty Comparing Air Versus 20% SF6 Tamponade.
Cornea. 2018;37(7): 834-839

Dannhausen K, Möhle C, Langmann T Immunomodulation with minocycline rescues retinal degeneration in juvenile neuronal ceroid lipofuscinosis mice highly susceptible to light damage. Dis Model Mech. 2018;11(9)

Akhtar-Schäfer I, Wang L, Krohne TU, Xu H, Langmann T Modulation of three key innate immune pathways for the most common retinal degenerative diseases. EMBO Mol Med. 2018;10(10)

Mor JM, Matthaei M, Schrumpf H, Koch KR, Bölke E, Heindl LM Transcanalicular laser dacryocystorhinostomy for acquired nasolacrimal duct obstruction: an audit of 104 patients. Eur J Med Res. 2018;23(1): 58

Enders P, Schaub F, Adler W, Hermann MM, Dietlein TS, Cursiefen C, Heindl LM, Medscape Bruch’s membrane opening-based optical coherence tomography of the optic nerve head: a useful diagnostic tool to detect glaucoma in macrodiscs. Eye. 2018;32(2): 314-323

Matthaei M, Elsner E, Caramoy A, Adler W, Siebelmann S, Schaub F, Skevas C, Liakopoulos S, Bachmann B, Cursiefen C, Heindl LM Fuchs endothelial corneal dystrophy and macular drusen: evidence for coincidence?
Eye. 2018;32(4): 840-841

Rashid K, Wolf A, Langmann T Microglia Activation and Immunomodulatory Therapies for Retinal Degenerations. Front Cell Neurosci. 2018;12: 176

Kasper M, Walscheid K, Laffer B, Bauer D, Busch M, Wildschütz L, Wang B, Loser K, Vogl T, Grajewski RS, Langmann T, Heiligenhaus A The Phenotype of Monocytes in Anterior Uveitis Depends on the HLA-B27 Status. Front Immunol. 2018;9: 1773

Van Schil K, Naessens S, Van de Sompele S, Carron M, Aslanidis A, Van Cauwenbergh C, Kathrin Mayer A, Van Heetvelde M, Bauwens M, Verdin H, Coppieters F, Greenberg ME, Yang MG, Karlstetter M, Langmann T, De Preter K, Kohl S, Cherry TJ, Leroy BP, CNV Study Group , De Baere E, Lupski JR, Carvalho C, van Min M, Klous P, De Jaegere S, Hooghe S Mapping the genomic landscape of inherited retinal disease genes prioritizes genes prone to coding and noncoding copy-number variations.
Genet Med. 2018;20(2): 202-213

Hoerster R, Cursiefen C, Streichert T, Heindl LM Impact of systemic inhibition on ocular levels of angiotensin-converting enzyme (ACE).
Graefes Arch Clin Exp Ophthalmol. 2018;256(12): 2487-2488

Rokohl AC, Koch KR, Adler W, Trester M, Trester W, Pine NS, Pine KR, Heindl LM Concerns of anophthalmic patients-a comparison between cryolite glass and polymethyl methacrylate prosthetic eye wearers. Graefes Arch Clin Exp Ophthalmol. 2018;256(6): 1203-1208

Schaub F, Adler W, Enders P, Koenig MC, Koch KR, Cursiefen C, Kirchhof B, Heindl LM Preexisting epiretinal membrane is associated with pseudophakic cystoid macular edema. Graefes Arch Clin Exp Ophthalmol. 2018;256(5): 909-917

Siebelmann S, Horstmann J, Scholz P, Bachmann B, Matthaei M, Hermann M, Cursiefen C Intraoperative changes in corneal structure during excimer laser phototherapeutic keratectomy (PTK) assessed by intraoperative optical coherence tomography.
Graefes Arch Clin Exp Ophthalmol. 2018;256(3): 575-581

Bukowiecki A, Cursiefen C, Eming SA, Hos D Phase-specific functions of macrophages in inflammatory corneal angiogenesis Invest Ophthalmol Vis Sci. 2018;59(9):

Clahsen T, Regenfuss B, Buttner C, Gabriel T, Bock F, Reis A, Cursiefen C Tyrosinase downregulates Fibromodulin- induced lymphangiogenesis
Invest Ophthalmol Vis Sci. 2018;59(9):

Di Pierdomenico J, Scholz R, Valiente-Soriano FJ, Sánchez-Migallón MC, Vidal-Sanz M, Langmann T, Agudo-Barriuso M, García-Ayuso D, Villegas-Pérez MP Neuroprotective Effects of FGF2 and Minocycline in Two Animal Models of Inherited Retinal Degeneration. Invest Ophthalmol Vis Sci. 2018;59(11): 4392-4403

Enders P, Adler W, El-Malahi O, Schaub F, Hermann M, Dietlein TS, Cursiefen C, Heindl LM Evaluation of three distinct diameter sizes for circular scanning of peripapillary retinal nerve fiber layer (pRNFL) thickness in glaucoma diagnostics
Invest Ophthalmol Vis Sci. 2018;59(9):

Hoerster R, Matthaei M, Cursiefen C, Tahmaz E, Streichert T, Refaian N, Heindl LM Ocular levels of angiotensin converting enzyme (ACE) in Fuchs’ Endothelial Dystrophy
Invest Ophthalmol Vis Sci. 2018;59(9

Hou YH, Le VNH, Toth G, Siebelmann S, Horstmann J, Gabriel T, Bock F, Cursiefen C Promotion of high-risk corneal graft survival via corneal UV-light crosslinking
Invest Ophthalmol Vis Sci. 2018;59(9

Klee K, Storti F, Dunaief JL, Langmann T, Grimm C Loss of Translocator Protein 18 kDa (TSPO) in the retinal pigment epithelium (RPE) of mice may lead to impaired visual function and abnormal RPE morphology Invest Ophthalmol Vis Sci. 2018;59(9):

Rashid K, Wolf A, Karlstetter M, Langmann T Microglia-specific expression of Translocator Protein (18kDa) Invest Ophthalmol Vis Sci. 2018;59(9

Reuer T, Schneider AC, Cakir B, Bühler AD, Walz JM, Lapp T, Lange C, Agostini H, Schlunck G, Cursiefen C, Reinhard T, Bock F, Stahl A Semaphorin 3F Modulates Corneal Lymphangiogenesis and Promotes Corneal Graft Survival. Invest Ophthalmol Vis Sci. 2018;59(12): 5277-5284

Siebelmann S, Ramos SL, Scholz P, Matthaei M, Schrittenlocher S, Heindl LM, Bachmann B, Cursiefen C Graft attachment after Descemet Membrane Endothelial Keratoplasty (DMEK) comparing two different anterior chamber tamponades Invest Ophthalmol Vis Sci. 2018;59(9):

Steven P, Schwab S, Saban DR, Niederkorn JY, Gehlsen U Role of Antigen-presenting Cells within Conjunctiva-associated Lymphoid Tissue in the Induction of Ocular Allergy Invest Ophthalmol Vis Sci. 2018;59(9):

Van Schil K, Naessens S, Van de Sompele S, Carron M, Lambrechts L, Roura NG, Dannhausen K, Coppieters F, Karlstetter M, Langmann T, Maroofian R, Webster A, Michaelides M, Leroy BP, De Baere E Leveraging consanguinity in inherited retinal diseases uncovers missing genetic variation: rare novel disease genes and a multitude of novel pathogenic variants in known disease genes Invest Ophthalmol Vis Sci. 2018;59(9):

Heindl LM, Adler W, El-Malahi O, Schaub F, Hermann MM, Dietlein TS, Cursiefen C, Enders P The Optimal Diameter for Circumpapillary Retinal Nerve Fiber Layer Thickness Measurement by SD-OCT in Glaucoma. J Glaucoma. 2018;27(12): 1086-1093
Guo Y, Shao C, Blau T, Tannapfel A, Koch KR, Heindl LM Ocular Metastasis of Bronchial Typical Carcinoid. J Thorac Oncol. 2018;13(9): 1422-1423

Lorés-Motta L, Riaz M, Grunin M, Corominas J, van Asten F, Pauper M, Leenders M, Richardson AJ, Muether P, Cree AJ, Griffiths HL, Pham C, Belanger MC, Meester-Smoor MA, Ali M, Heid IM, Fritsche LG, Chakravarthy U, Gale R, McKibbin M, Inglehearn CF, Schlingemann RO, Omar A, Chen J, Koenekoop RK, Fauser S, Guymer RH, Hoyng CB, de Jong EK, Lotery AJ, Mitchell P, den Hollander AI, Baird PN, Chowers I Association of Genetic Variants With Response to Anti-Vascular Endothelial Growth Factor Therapy in Age-Related Macular Degeneration. JAMA Ophthalmol. 2018;136(8): 875-884

Cursiefen C, Heiligenhaus A Treatment Concepts for Patients with Non-infectious Uveitis
Klin Monatsbl Augenheilkd. 2018;235(5): 551-552

Kakkassery V, Heindl LM SOP Standardized Procedure in the Diagnosis and Treatment of periocular Basal Cell Carcinoma Klin Monatsbl Augenheilkd. 2018;235(1): 15-22

Kopecky A, Rokohl AC, Heindl LM Reconstruction Techniques of the posterior Eyelid Lamella Klin Monatsbl Augenheilkd. 2018;235(12): 1415-1426

Kopecky A, Nemcansky J, Koch KR, Heindl LM Otto Wichterle and Soft Contact Lenses Klin Monatsbl Augenheilkd. 2018;235(12): 1411-1413)

Siebelmann S, Matthaei M, Heindl LM, Bachmann BO, Cursiefen C Intraoperative Optical Coherence Tomography (MI-OCT) for the Treatment of Corneal Dystrophies Klin Monatsbl Augenheilkd. 2018;235(6): 714-720

Rokohl AC, Koch KR, Trester M, Trester W, Pine KR, Heindl LM Concerns of Anophthalmic Patients Wearing Cryolite Glass Prosthetic Eyes.
Ophthal Plast Reconstr Surg. 2018;34(4): 369-374

Avgitidou G, Heindl LM, Cursiefen C [Block excision with tectonic corneoscleral graft for traumatic pediatric epithelial implantation cysts]. Ophthalmologe. 2018;115(1): 67-70

Cursiefen C Endothelial Immune Response after DMEK: what is the Risk? Ophthalmologe. 2018;115(12): 1018-1018

Cursiefen C IOL Calcification in hydrophilic Acrylic Lenses Ophthalmologe. 2018;115(12): 1019-1019

Cursiefen C NGF Eye Drops: REPARO Study Ophthalmologe. 2018;115(12): 1019-1019

Cursiefen C DMEK more beneficial than DSAEK Ophthalmologe. 2018;115(12): 1018-1018

Glossmann JP, Skoetz N, Starbatty B, Bischoff M, Leyvraz S, Westekemper H, AG SOP , Unter-AG Konjunktivales Melanom , Heindl LM, Materna V, Troost E, Noak K, Benito Rabenort M, Palm S, Kemink T, Degener K, Reimer C, Schafhausen P, Dietrich M, Hale K, Scheid C, Schneider V, Pretzell EI, Dorn J, Böck S, Kraus-Pfeiffer G, Seckinger A, Sommer R, Schauer U, Krein A, Meier F, Sommer F, Kreis S, Richly H, Bauer S, Griewank K, Hrgovic I, Meissner M, Wolff R, Auw-Hädrich C, Reinhard T, von Bubnoff D, Fuisting B, Staub J, Hassel JC, Marnitz-Schulze KS, Schlaak M, Laspas P, Loquai C, Siedlecki J, Süsskind D, Paulsen F, Eigentler T, Treiber N, Ach T, Gesierich A, Kampik D [Conjunctival melanoma : Standard operating procedures in diagnosis, treatment and follow-up care]. Ophthalmologe. 2018;115(6): 489-498

Hos D Training in Ophthalmology in Germany Ophthalmologe. 2018;115(6): 530-530

Le Blanc C, Rokohl AC, Grajewski RS, Ortmann M, Koch KR, Heindl LM [Acute onset of ptosis in a 23-year-old female patient].
Ophthalmologe. 2018;115(9): 769-772

Matthaei M, Bachmann B, Siebelmann S, Cursiefen C [Technique of Descemet membrane endothelial keratoplasty (DMEK) : Video article].
Ophthalmologe. 2018;115(9): 778-784

Mor JM, Semrau R, Baus W, Koch KR, Schaub F, Cursiefen C, Marnitz S, Heindl LM [CyberKnife®: new treatment option for uveal melanoma].
Ophthalmologe. 2018;115(4): 302-308

Rokohl AC, Koch KR, Trester M, Heindl LM [Cryolite glass ocular prostheses and coralline hydroxyapatite implants for eye replacement following enucleation]. Ophthalmologe. 2018;115(9): 793-794

Schaub F, Neuhann I, Enders P, Bachmann BO, Koller B, Neuhann T, Cursiefen C [Boston keratoprosthesis: 73 eyes from Germany : An overview of experiences from two centers]. Ophthalmologe. 2018;115(9): 744-753

Siebelmann S, Bachmann B, Matthaei M, Horstmann J, Dietlein T, Lappas A, Scholz P, Cursiefen C [Microscope-integrated intraoperative optical coherence tomography in examination of pediatric patients under anesthesia]. Ophthalmologe. 2018;115(9): 785-792

Beck SC, Karlstetter M, Garcia Garrido M, Feng Y, Dannhausen K, Mühlfriedel R, Sothilingam V, Seebauer B, Berger W, Hammes HP, Seeliger MW, Langmann T Cystoid edema, neovascularization and inflammatory processes in the murine Norrin-deficient retina. Sci Rep. 2018;8(1): 5970

Le VNH, Schneider AC, Scholz R, Bock F, Cursiefen C Fine Needle-Diathermy Regresses Pathological Corneal (Lymph)Angiogenesis and Promotes High-Risk Corneal Transplant Survival. Sci Rep. 2018;8(1): 5707

Madeira MH, Rashid K, Ambrósio AF, Santiago AR, Langmann T Blockade of microglial adenosine A2A receptor impacts inflammatory mechanisms, reduces ARPE-19 cell dysfunction and prevents photoreceptor loss in vitro.
Sci Rep. 2018;8(1): 2272

Notara M, Behboudifard S, Kluth MA, Maßlo C, Ganss C, Frank MH, Schumacher B, Cursiefen C UV light-blocking contact lenses protect against short-term UVB-induced limbal stem cell niche damage and inflammation. Sci Rep. 2018;8(1): 12564

Mehlan J, Steinberg J, Katz T, Cursiefen C, Keseru M, Linke SJ PACK-CXL for severe keratitis in a young patient with ichthyosis Spektrum Augenheilkunde. 2018;32(4-5): 194-197

Notara M, Lentzsch A, Coroneo M, Cursiefen C The Role of Limbal Epithelial Stem Cells in Regulating Corneal (Lymph)angiogenic Privilege and the Micromilieu of the Limbal Niche following UV Exposure. Stem Cells Int. 2018;2018: 8620172

Siebelmann S, Scholz P, Sonnenschein S, Bachmann B, Matthaei M, Cursiefen C, Heindl LM Anterior segment optical coherence tomography for the diagnosis of corneal dystrophies according to the IC3D classification. Surv Ophthalmol. 2018;63(3): 365-380

2017

Caramoy A, Engel L, Koch KR, Kirchhof B, Cursiefen C, Heindl LM Multiple imaging modalities for the detection of optic nerve head drusen: Is echography still mandatory? Acta Ophthalmol. 2017;95(3): 320-323

Grajewski RS, Barahmand Pour N, Burian K, Caramoy A, Kirchhof B, Cursiefen C, Heindl LM Analysis of the impact of allergy and atopy on new onset of uveitis.
Acta Ophthalmol. 2017;95(3): e236-e241

Grajewski RS, Heindl LM Macular thickening of uveitic eyes in the absence of macular oedema and epiretinal membranes. Acta Ophthalmol. 2017;95(1): e77-e78

Schaub F, Enders P, Roters S, Cursiefen C, Bachmann BO Single-pass Ultrathin DSAEK (UT-DSAEK) with the SLc Expert Microkeratome. Acta Ophthalmol. 2017;95(2): e160-e161

Enders P, Schaub F, Heindl LM Spectral-Domain Optical Coherence Tomography-Derived Characteristics of Bruch Membrane Opening in a Young Adult Australian Population. Am J Ophthalmol. 2017;174: 178-179

Schaub F, Enders P, Bluhm C, Bachmann BO, Cursiefen C, Heindl LM Two-Year Course of Corneal Densitometry After Descemet Membrane Endothelial Keratoplasty. Am J Ophthalmol. 2017;175: 60-67

Schrittenlocher S, Penier M, Schaub F, Bock F, Cursiefen C, Bachmann B Intraocular Lens Calcifications After (Triple-) Descemet Membrane Endothelial Keratoplasty. Am J Ophthalmol. 2017;179: 129-136

Avgitidou G, Koch KR, Heindl LM Minimally Invasive Therapy of Lacrimal Duct Stenoses
Augenheilkund Up2date. 2017;7(3): 203-213

Kakkassery V, Heindl LM SOP Standardized Procedure in the Diagnosis and Therapy of the periocular Basal Cell Carcinoma Augenheilkund Up2date. 2017;7(3): 185-192

Mor JM, Koch KR, Heindl LM Diagnosis and Therapy of Iris Lesions Augenheilkund Up2date. 2017;7(4): 315-326
Tahmaz V, Radojska S, Cursiefen C, Gathof B, Steven SOP Autologous Serum Suction Drops – Indication, Manufacture, Application Augenheilkund Up2date. 2017;7(1): 10-14 P

Schaub F, Enders P, Adler W, Bachmann BO, Cursiefen C, Heindl LM Impact of donor graft quality on deep anterior lamellar Keratoplasty (DALK). BMC Ophthalmol. 2017;17(1): 204

Nebel C, Aslanidis A, Rashid K, Langmann T Activated microglia trigger inflammasome activation and lysosomal destabilization in human RPE cells. Biochem Biophys Res Commun. 2017;484(3): 681-686 (Impact(2016)=2.466, Typ=Article; Journal Article; Research Support, Non-U.S. Gov’t)

Wolf A, Aslanidis A, Langmann T Retinal expression and localization of Mef2c support its important role in photoreceptor gene expression. Biochem Biophys Res Commun. 2017;483(1): 346-351

Enders P, Schaub F, Hermann MM, Cursiefen C, Heindl LM Neuroretinal rim in non-glaucomatous large optic nerve heads: a comparison of confocal scanning laser tomography and spectral domain optical coherence tomography.
Br J Ophthalmol. 2017;101(2): 138-142

Enders P, Schaub F, Adler W, Nikoluk R, Hermann MM, Heindl LM The use of Bruch’s membrane opening-based optical coherence tomography of the optic nerve head for glaucoma detection in microdiscs. Br J Ophthalmol. 2017;101(4): 530-535

Hong J, Yang Y, Cursiefen C, Mashaghi A, Wu D, Liu Z, Sun X, Dana R, Xu J Optimising keratoplasty for Peters’ anomaly in infants using spectral-domain optical coherence tomography. Br J Ophthalmol. 2017;101(6): 820-827

Schaub F, Enders P, Snijders K, Schrittenlocher S, Siebelmann S, Heindl LM, Bachmann BO, Cursiefen C One-year outcome after Descemet membrane endothelial keratoplasty (DMEK) comparing sulfur hexafluoride (SF) 20% versus 100% air for anterior chamber tamponade. Br J Ophthalmol. 2017;101(7): 902-908

Tahmaz V, Gehlsen U, Sauerbier L, Holtick U, Engel L, Radojska S, Petrescu-Jipa VM, Scheid C, Hallek M, Gathof B, Cursiefen C, Steven P Treatment of severe chronic ocular graft-versus-host disease using 100% autologous serum eye drops from a sealed manufacturing system: a retrospective cohort study.
Br J Ophthalmol. 2017;101(3): 322-326

Subiras X, Koch KR, Schrittenlocher S, Cursiefen C, Heindl LM Spontaneous Unilateral Subperiosteal Hematoma in the Orbit due to Self-Induced Asphyxia: Unusual Cause of Unilateral Exophthalmos. Case Rep Ophthalmol. 2017;8(1): 232-236

Caramoy A, Heindl LM Variability of choroidal and retinal thicknesses in healthy eyes using swept-source optical coherence tomography – implications for designing clinical trials. Clin Ophthalmol. 2017;11: 1835-1839 (

Enders P, Holtick U, Schaub F, Tuchscherer A, Hermann MM, Scheid C, Cursiefen C, Bachmann BO Corneal Densitometry for Quantification of Corneal Deposits in Monoclonal Gammopathies. Cornea. 2017;36(4): 470-475

Siebelmann S, Matthaei M, Hörster R, Cursiefen C, Bachmann B Lutein and Brilliant Blue-Based Dye for Donor Preparation and Transplantation in Descemet Membrane Endothelial Keratoplasty. Cornea. 2017;36(4): 440-444

Martens TF, Peynshaert K, Nascimento TL, Fattal E, Karlstetter M, Langmann T, Picaud S, Demeester J, De Smedt SC, Remaut K, Braeckmans K Effect of hyaluronic acid-binding to lipoplexes on intravitreal drug delivery for retinal gene therapy. Eur J Pharm Sci. 2017;103: 27-35

Storti F, Raphael G, Griesser V, Klee K, Drawnel F, Willburger C, Scholz R, Langmann T, von Eckardstein A, Fingerle J, Grimm C, Maugeais C Regulated efflux of photoreceptor outer segment-derived cholesterol by human RPE cells. Exp Eye Res. 2017;165: 65-77

Schick T, Steinhauer M, Aslanidis A, Altay L, Karlstetter M, Langmann T, Kirschfink M, Fauser S Local complement activation in aqueous humor in patients with age-related macular degeneration. Eye. 2017;31(5): 810-813

Akhtar I, Langmann T Role of HtrA1 in TGF beta signaling and microglia quiescence Glia. 2017;65 1: E456-E456

Rashid K, Scholz R, Karlstetter M, Wolf A, Langmann T Microglia-specific expression of translocator protein (18kDa) (TSPO) Glia. 2017;65 1: E231-E231

Shahraz A, Kopatz J, Linnartz-Gerlach B, Karlstetter M, Aslanidis A, Langmann T, de Fries I, Beutel S, Scheper T, Neumann H Inhibition of innate immunity by low molecular weight polysialic acid as a novel therapy approach for age related macular degeneration Glia. 2017;65 1: E70-E70

Gehlsen U, Braun T, Notara M, Krösser S, Steven P A semifluorinated alkane (F4H5) as novel carrier for cyclosporine A: a promising therapeutic and prophylactic option for topical treatment of dry eye.
Graefes Arch Clin Exp Ophthalmol. 2017;255(4): 767-775

Hoerster R, Fauser S, Cursiefen C, Kirchhof B, Heindl LM The influence of systemic renin-angiotensin-inhibition on ocular cytokines related to proliferative vitreoretinopathy Graefes Arch Clin Exp Ophthalmol. 2017;255(9): 1721-1725

Schaub F, Pohl L, Enders P, Adler W, Bachmann BO, Cursiefen C, Heindl LM Impact of corneal donor lens status on two-year course and outcome of Descemet membrane endothelial keratoplasty (DMEK). Graefes Arch Clin Exp Ophthalmol. 2017;255(12): 2407-2414

Schaub F, Enders P, Bachmann BO, Heindl LM, Cursiefen C Effect of corneal collagen crosslinking on subsequent deep anterior lamellar keratoplasty (DALK) in keratoconus. Graefes Arch Clin Exp Ophthalmol. 2017;255(4): 811-816

Bukowiecki A, Hos D, Cursiefen C, Eming SA Wound-Healing Studies in Cornea and Skin: Parallels, Differences and Opportunities
Int J Mol Sci. 2017;18(6): 1257

Enders P, Bremen A, Schaub F, Hermann MM, Diestelhorst M, Dietlein T, Cursiefen C, Heindl LM Intraday Repeatability of Bruch’s Membrane Opening-Based Neuroretinal Rim Measurements. Invest Ophthalmol Vis Sci. 2017;58(12): 5195-5200

Horstmann J, Schulz-Hildebrandt H, Bock F, Siebelmann S, Lankenau E, Hüttmann G, Steven P, Cursiefen C Label-Free In Vivo Imaging of Corneal Lymphatic Vessels Using Microscopic Optical Coherence Tomography. Invest Ophthalmol Vis Sci. 2017;58(13): 5880-5886

Buj C, Munter M, Schmarbeck B, Horstmann J, Huttmann G, Brinkmann R Noncontact holographic detection for photoacoustic tomography J Biomed Opt. 2017;22(10): 106007

Schaub F, Adler W, Koenig MC, Enders P, Dietlein TS, Cursiefen C, Heindl LM Combined Ab Interno Glaucoma Surgery Does not Increase the Risk of Pseudophakic Cystoid Macular Edema in Uncomplicated Eyes. J Glaucoma. 2017;26(3): 227-232

Micklisch S, Lin Y, Jacob S, Karlstetter M, Dannhausen K, Dasari P, von der Heide M, Dahse HM, Schmölz L, Grassmann F, Alene M, Fauser S, Neumann H, Lorkowski S, Pauly D, Weber BH, Joussen AM, Langmann T, Zipfel PF, Skerka C Age-related macular degeneration associated polymorphism rs10490924 in ARMS2 results in deficiency of a complement activator. J Neuroinflammation. 2017;14(1): 4

Mor JM, Guo YW, Koch KR, Heindl LM Transcanalicular Diode Laser-assisted Dacryocystorhinostomy for the Treatment of Primary Acquired Nasolacrimal Duct Obstruction J Vis Exp. 2017;-(128): e55981

Avgitidou G, Koch KR, Heindl LM Minimal Invasive Therapy of Dacryostenosis Klin Monatsbl Augenheilkd. 2017;234(9): 1183-1193

Bachmann BO, Schrittenlocher SA, Schaub F, Siebelmann S, Matthaei M, Cursiefen C Complications of DMEKeratoplasty: Avoid, Recognize and Treat
Klin Monatsbl Augenheilkd. 2017;234(11): 1354-1361

Bosch JJ, Heindl LM Novel Adjuvant Therapy for Ocular Melanoma Klin Monatsbl Augenheilkd. 2017;234(5): 670-673

Cursiefen C, Heiligenhaus A Klin Monatsbl Augenheilkd. 2017;234(5): 650-651 (Material)

Drozhzhyna GI, Gaidamaka TB, Cursiefen C, Bachmann BO, Ivanovska OV, Ostashevsky VL, Kogan B, Usov VJ, Pasyechnikova NV Emergency Keratoplasty with Porcine Xenografts in Necrotizing Keratitis Klin Monatsbl Augenheilkd. 2017;234(11): 1387-1395

Khatib R, Koch KR, Heindl LM Electrical Cataract after Electrical Injuries Klin Monatsbl Augenheilkd. 2017;234(8): 986-987

Mor JM, Koch KR, Heindl LM Diagnosis and Treatment of Iris Lesions Klin Monatsbl Augenheilkd. 2017;234(12): 1541-1552

Sauerbier L, Kirschke R, Tahmaz V, Steven P Adaptation of Dressing Contact Lenses – step by step Klin Monatsbl Augenheilkd. 2017;234(12): 1438-1442

Schaub F, Bachmann BO, Seyeddain O, Moussa S, Reitsamer HA, Cursiefen C Mid- and Longterm Experiences with the Boston-Keratoprosthesis. The Cologne and Salzburg Perspective Klin Monatsbl Augenheilkd. 2017;234(6): 770-775

Steven P, Braun T, Krosser S, Gehlsen U Influence of Aging on Severity and Anti-Inflammatory Treatment of Experimental Dry Eye Disease Klin Monatsbl Augenheilkd. 2017;234(5): 662-669

Tahmaz V, Radojska S, Cursiefen C, Gathof B, Steven P SOP/Workflow SOP Autologous Serum Eye Drops – Indication, Manufacture, Application Klin Monatsbl Augenheilkd. 2017;234(2): 162-165

Karlstetter M, Dannhausen K, Langmann T Microglia and immunomodulatory therapies for retinal degenerative diseases Med Genet. 2017;29(2): 225-233

Koch KR, Hishmi AM, Ortmann M, Heindl LM Uveal Melanoma Cell Seeding after Transretinal Tumor Biopsy? Ocul Oncol Pathol. 2017;3(3): 164-167

Mor JM, Heindl LM Systemic BRAF/MEK Inhibitors as a Potential Treatment Option in Metastatic Conjunctival Melanoma. Ocul Oncol Pathol. 2017;3(2): 133-141

Osae AE, Gehlsen U, Horstmann J, Siebelmann S, Stern ME, Kumah DB, Steven P Epidemiology of dry eye disease in Africa: The sparse information, gaps and opportunities. Ocul Surf. 2017;15(2): 159-168

Glossmann JP, Heindl L, Leyvraz S, Starbatty B, Bischoff M, Skoetz N Standards for the diagnosis, therapy and follow-up of a rare cancer: development of a network-SOP for conjunctival melanoma Oncol Res Treat. 2017;40 3: 7-7

Cursiefen C Dry Eye, Pain, Depression and Sleep Disorders Ophthalmologe. 2017;114(6): 494-494

Grajewski RS, Heindl LM [Paraneoplastic serous retinopathies: hormones, mediators, and inhibitors]. Ophthalmologe. 2017;114(4): 377-378

Heindl LM [Update on minimally invasive lacrimal drainage surgery]. Ophthalmologe. 2017;114(5): 396

Hoerster R, Schlaak M, Koch KR, Ortmann M, Mauch C, Heindl LM [Merkel cell carcinoma of the eyelid. An often unrecognized tumor entity : Clinical aspects and treatment strategies]. Ophthalmologe. 2017;114(2): 134-139

Hoerster R, Stanzel TP Prophylaxis of the cystic Macular Edema after DMEK Ophthalmologe. 2017;114(6): 495-495

Joachim SC, Prokosch V, Hos D, Sprecher AG Young Dog Time and Money: Resources for Your Research Symposium of the AG Young DOG Ophthalmologe. 2017;114(12): 1169-1170

Kakkassery V, Loeffler KU, Sand M, Koch KR, Lentzsch AM, Nick AC, Adamietz IA, Heindl LM [Current diagnostics and therapy recommendations for ocular basal cell carcinoma].
Ophthalmologe. 2017;114(3): 224-236

Koch KR, Cursiefen C, Heindl LM [Minimally invasive bypass surgery for nasolacrimal duct obstruction : Transcanalicular laser-assisted dacryocystorhinostomy]. Ophthalmologe. 2017;114(5): 416-423

Kopecky A, Koch KR, Heindl LM [Uncommon inflammation of the upper eyelid].
Ophthalmologe. 2017;114(9): 848-850

Prokosch-Willing V, Hos D, Joachim SC [Research during residency].
Ophthalmologe. 2017;114(10): 901-905

Schaub F, Heindl LM, Enders P, Roters S, Bachmann BO, Cursiefen C [Deep Anterior Lamellar Keratoplasty : Experiences and results of the first 100 consecutive DALK from the University Eye Hospital of Cologne]. Ophthalmologe. 2017;114(11): 1019-1026

Schlötzer-Schrehardt U, Cursiefen C [Basic research in ophthalmology in Germany and its international context]. Ophthalmologe. 2017;114(9): 804-811

Schrittenlocher S, Bachmann B, Cursiefen C [Heterochromia and unilateral iris nodules]. Ophthalmologe. 2017;114(3): 269-271

Hoerster R, Cursiefen C Re: Kitazawa et al.: Cystoid macular edema after Descemet’s stripping automated endothelial keratoplasty (Ophthalmology. 2017;124:572-573). Ophthalmology. 2017;124(12): e86

Enders P, Adler W, Schaub F, Hermann MM, Diestelhorst M, Dietlein T, Cursiefen C, Heindl LM Optimization Strategies for Bruch’s Membrane Opening Minimum Rim Area Calculation: Sequential versus Simultaneous Minimization. Sci Rep. 2017;7(1): 13874

Hos D, Bukowiecki A, Horstmann J, Bock F, Bucher F, Heindl LM, Siebelmann S, Steven P, Dana R, Eming SA, Cursiefen C Transient Ingrowth of Lymphatic Vessels into the Physiologically Avascular Cornea Regulates Corneal Edema and Transparency. Sci Rep. 2017;7(1): 7227

Gathof B, Homann N, Mrotzek M, Petrescu-Jipa VM, Stormer M, Steven P, Cursiefen C, Radojska S Autologous serum eye drops: five years experience of manufacturing
Transfus Med Hemother. 2017;44 1: 85-86

Mrotzek M, Homann N, Petrescu-Jipa VM, Radojska S, Steven P, Cursiefen C, Stormer M, Gathof B Serum eye drops: first experience of manufacturing and treatment in allogeneic setting Transfus Med Hemother. 2017;44 1: 87-87

Lorenz K, Scheller Y, Bell K, Grus F, Ponto KA, Bock F, Cursiefen C, Flach J, Gehring M, Peto T, Silva R, Tal Y, Pfeiffer N A prospective, randomised, placebo-controlled, double-masked, three-armed, multicentre phase II/III trial for the Study of a Topical Treatment of Ischaemic Central Retinal Vein Occlusion to Prevent Neovascular Glaucoma – the STRONG study: study protocol f Trials. 2017;18(1): 128

Hou Y, Le VNH, Clahsen T, Schneider AC, Bock F, Cursiefen C (2017). Photodynamic Therapy Leads to Time-Dependent Regression of Pathologic Corneal (Lymph)Angiogenesis and Promotes High-Risk Corneal Allograft Survival. Invest Ophthalmol Vis Sci. Nov 1;58(13):5862-5869.

Lückoff A, Scholz R, Sennlaub F, Xu H, Langmann T. Comprehensive analysis of mouse retinal mononuclear phagocytes. Nat Protoc. 2017 Jun;12(6):1136-1150.

Matthaei M, Sandhaeger H, Hermel M, Adler W, Jun AS, Cursiefen C, Heindl LM. Changing Indications in Penetrating Keratoplasty: A Systematic Review of 34 Years of Global Reporting. Transplantation. 2017 Jun;101(6):1387-1399.

Cursiefen C, Heiligenhaus A. [“Translational Research in Ophthalmology is Important!”]. Klin Monbl Augenheilkd. 2017 May;234(5):650-651.

Langmann T, Fauser S. [Polysialic Acid for Immunomodulation in an Animal Model for Wet Age-Related Macular Degeneration (AMD)]. Klin Monbl Augenheilkd. 2017 May;234(5):657-661.

Steven P, Braun T, Krösser S, Gehlsen U. [Influence of Aging on Severity and Anti-Inflammatory Treatment of Experimental Dry Eye Disease]. Klin Monbl Augenheilkd. 2017 May;234(5):662-669.

Bock F, Cursiefen C. [Anti(lymph)angiogenic Strategies to Improve Corneal Graft Survival]. Klin Monbl Augenheilkd. 2017 May;234(5):674-678.

Cursiefen C, Bock F, Clahsen T, Regenfuss B, Reis A, Steven P, Heindl LM, Bosch JJ, Hos D, Eming S, Grajewski R, Heiligenhaus A, Fauser S, Austin J, Langmann T. [New Therapeutic Approaches in Inflammatory Diseases of the Eye – Targeting Lymphangiogenesis and Cellular Immunity: Research Unit FOR 2240 Presents Itself]. Klin Monbl Augenheilkd. 2017 May;234(5):679-685.

Schick T, Steinhauer M, Aslanidis A, Altay L, Karlstetter M, Langmann T, Kirschfink M, Fauser S. Local complement activation in aqueous humor in patients  with age-related macular degeneration. Eye (Lond). 2017 May;31(5):810-813.

Hos D, Tuac O, Schaub F, Stanzel TP, Schrittenlocher S, Hellmich M, Bachmann BO, Cursiefen C. Incidence and Clinical Course of Immune Reactions after Descemet Membrane Endothelial Keratoplasty: Retrospective Analysis of 1000 Consecutive Eyes. Ophthalmology. 2017 Apr;124(4):512-518.

Heindl LM, Koch KR, Hermann MM, Merkelbach-Bruse S, Schultheis AM, Wagener S, Büttner R, Mauch C, Schuler-Thurner B, Schuler G, Cursiefen C. Block Excision of  Iridociliary Tumors Enables Molecular Profiling and Immune Vaccination. Ophthalmology. 2017 Feb;124(2):268-270.

Karlstetter M, Kopatz J, Aslanidis A, Shahraz A, Caramoy A, Linnartz-Gerlach B, Lin Y, Lückoff A, Fauser S, Düker K, Claude J, Wang Y, Ackermann J, Schmidt T, Hornung V, Skerka C, Langmann T*, Neumann H*. Polysialic acid blocks mononuclear phagocyte reactivity, inhibits complement activation, and protects from vascular damage in the retina. EMBO Mol Med. 2017 Feb;9(2):154-166.*shared senior authors.

Horstmann J, Siebelmann S, Schulz-Hildebrandt H, Glasunow I, Schadschneider A, Hüttmann G. [Understanding OCT – Part 2: State of the Practice]. Klin Monbl Augenheilkd. 2017 Feb;234(2):233-247.

Horstmann J, Siebelmann S, Schulz-Hildebrandt H, Glasunow I, Schadschneider A, Hüttmann G. [Understanding OCT – Part 1: Basic Knowledge]. Klin Monbl Augenheilkd. 2017 Jan;234(1):131-143.

Böhm MR, Tappeiner C, Breitbach MA, Zurek-Imhoff B, Heinz C, Heiligenhaus A. Ocular Hypotony in Patients With Juvenile Idiopathic Arthritis-Associated Uveitis. Am J Ophthalmol. 2017 Jan;173:45-55.

2016

Bock F, Onderka J, Braun G, Schneider A-S, Hos D, Bi Y, Bachmann B, Cursiefen C (2016). Identification of novel endogenous anti(lymph)angiogenic factors in the aqueous humor. Invest Ophthalmol Vis Sci. Dec 1;57(15):6554-6560

Scholz R, Langmann T. Gut flora connects obesity with pathological angiogenesis in the eye. EMBO Mol Med. 2016 Dec 1;8(12):1361-1363.

Boppudi S, Bögershausen N, Hove HB, Percin EF, Aslan D, Dvorsky R, Kayhan G, Li Y, Cursiefen C, Tantcheva-Poor I, Toft PB, Bartsch O, Lissewski C, Wieland I, Jakubiczka S, Wollnik B, Ahmadian MR, Heindl LM, Zenker M. Specific mosaic KRAS mutations affecting codon 146 cause oculoectodermal syndrome and encephalocraniocutaneous lipomatosis. Clin Genet. 2016 Oct;90(4):334-42.

Walscheid K, Weinhage T, Foell D, Heinz C, Kasper M, Heiligenhaus A. Phenotypic changes of peripheral blood mononuclear cells upon corticosteroid treatment in idiopathic intermediate uveitis. Clin Immunol. 2016 Oct 28. pii: S1521-6616(16)30534-4. [Epub ahead of print].

Schlereth SL, Kremers S, Schrödl F, Cursiefen C, Heindl LM. Characterization of Antigen-Presenting Macrophages and Dendritic Cells in the Healthy Human Sclera. Invest Ophthalmol Vis Sci. 2016 Sep 1;57(11):4878-4885.

Jaffe GJ, Dick AD, Brézin AP, Nguyen QD, Thorne JE, Kestelyn P, Barisani-Asenbauer T, Franco P, Heiligenhaus A, Scales D, Chu DS, Camez A, Kwatra NV, Song AP, Kron M, Tari S, Suhler EB. Adalimumab in Patients with Active Noninfectious Uveitis. N Engl J Med. 2016 Sep 8;375(10):932-43.

Altay L, Scholz P, Schick T, Felsch M, Hoyng CB, den Hollander AI, Langmann T, Fauser S. Association of Hyperreflective Foci Present in Early Forms of Age-Related Macular Degeneration With Known Age-Related Macular Degeneration Risk Polymorphisms. Invest Ophthalmol Vis Sci. 2016 Aug;57(10):4315-20.

Lückoff A, Caramoy A, Scholz R, Prinz M, Kalinke U, Langmann T. Interferon-beta signaling in retinal mononuclear phagocytes attenuates pathological neovascularization. EMBO Mol Med. 2016 Jun 1;8(6):670-8.

Matthaei M, Sandhaeger H, Hermel M, Adler W, Jun AS, Cursiefen C, Heindl LM. Changing Indications in Penetrating Keratoplasty: A Systematic Review of 34 Years of Global Reporting. Transplantation. 2016 Jun 22. [Epub ahead of print].

Hos D, Dörrie J, Schaft N, Bock F, Notara M, Kruse FE, Krautwald S, Cursiefen C, Bachmann BO. Blockade of CCR7 leads to decreased dendritic cell migration to draining lymph nodes and promotes graft survival in low-risk corneal transplantation. Exp Eye Res. 2016 May;146:1-6.

Koch KR, Ortmann M, Heindl LM. Conjunctival Mucoepidermoid Carcinoma. Ophthalmology. 2016 Mar;123(3):616.

Notara M, Refaian N, Braun G, Steven P, Bock F, Cursiefen C. Short-Term Ultraviolet A Irradiation Leads to Dysfunction of the Limbal Niche Cells and an Antilymphangiogenic and Anti-inflammatory Micromilieu. Invest Ophthalmol Vis Sci. 2016 Mar;57(3):928-39.

Grajewski RS, Bosch JJ, Bruns H, Cursiefen C, Heindl LM. The Trojan Horse Tale Revisited: An Eye on Metastatic Spread of Carcinoma Cells. Cancer Immunol Res. 2016 Feb;4(2):92-4.

Fritsche LG et al., Langmann T, et al., Heid IM. Insights into Rare and Common Genetic Variation From a Large Study of Age-Related Macular Degeneration. Nat Genet. 2016 Feb; 48:134-43.

Hos D, Bucher F, Regenfuss B, Dreisow ML, Bock F, Heindl LM, Eming SA, Cursiefen C. IL-10 Indirectly Regulates Corneal Lymphangiogenesis and Resolution of Inflammation via Macrophages. Am J Pathol. 2016 Jan;186(1):159-71.

Tappeiner C, Schenck S, Niewerth M, Heiligenhaus A, Minden K, Klotsche J. Impact of Antiinflammatory Treatment on the Onset of Uveitis in Juvenile Idiopathic Arthritis: Longitudinal Analysis From a Nationwide Pediatric Rheumatology Database. Arthritis Care Res (Hoboken). 2016 Jan;68(1):46-54.

Lückoff A, Scholz R, Sennlaub F, Xu H, Langmann T. Comprehensive analysis of retinal mononuclear phagocytes. Nature Protocols 2016; in press.

2015

Koch KR, Ortmann M, Heindl LM. Extraocular Extension of a Benign Ciliary Body Nevus. JAMA Ophthalmol. 2015 Dec;133(12).

Schuler-Thurner B, Bartz-Schmidt KU, Bornfeld N, Cursiefen C, Fuisting B, Grisanti S, Heindl LM, Holbach L, Keserü M, Knorr H, Koch K, Kruse F, Meiller R,  Metz C, Meyer-ter-Vehn T, Much M, Reinsberg M, Schliep S, Seitz B, Schuler G, Süsskind D, Viestenz A, Wagenfeld L, Zeschnigk M. [Immunotherapy of uveal melanoma: vaccination against cancer. Multicenter adjuvant phase 3 vaccination study using dendritic cells laden with tumor RNA for large newly diagnosed uveal  melanoma]. Ophthalmologe. 2015 Dec;112(12):1017-21.

Walscheid K, Heiligenhaus A, Holzinger D, Roth J, Heinz C, Tappeiner C, Kasper M, Foell D. Elevated S100A8/A9 and S100A12 Serum Levels Reflect Intraocular Inflammation in Juvenile Idiopathic Arthritis-Associated Uveitis: Results From a Pilot Study. Invest Ophthalmol Vis Sci. 2015 Dec;56(13):7653-60.

Notara M, Refaian N, Braun G, Steven P, Bock F, Cursiefen C. Short-term uvb-irradiation leads to putative limbal stem cell damage and niche cell-mediated upregulation of macrophage recruiting cytokines. Stem Cell Res. 2015 Nov;15(3):643-54.

Schrödl F, Kaser-Eichberger A, Trost A, Strohmaier C, Bogner B, Runge C, Motloch K, Bruckner D, Laimer M, Heindl LM, Reitsamer HA. Lymphatic Markers in the Adult Human Choroid. Invest Ophthalmol Vis Sci. 2015 Nov;56(12):7406-16

Heindl LM, Kaser-Eichberger A, Schlereth SL, Bock F, Regenfuss B, Reitsamer HA, McMenamin P, Lutty GA, Maruyama K, Chen L, Dana R, Kerjaschki D, Alitalo K, De Stefano ME, Junghans BM, Schroedl F, Cursiefen C. Sufficient Evidence for Lymphatics in the Developing and Adult Human Choroid? Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6709-10.

Siebelmann S, Steven P, Cursiefen C. Intraoperative Optical Coherence Tomography: Ocular Surgery on a Higher Level or Just Nice Pictures? JAMA Ophthalmol. 2015 Oct;133(10):1133-4.

Schlereth SL, Iden S, Mescher M, Ksander BR, Bosch JJ, Cursiefen C, Heindl LM. A Novel Model of Metastatic Conjunctival Melanoma in Immune-Competent Mice. Invest Ophthalmol Vis Sci. 2015 Sep;56(10):5965-73.

Bucher F, Schneider C, Blau T, Cursiefen C, Fink GR, Lehmann HC, Heindl LM. Small-Fiber Neuropathy Is Associated With Corneal Nerve and Dendritic Cell Alterations: An In Vivo Confocal Microscopy Study. Cornea. 2015 Sep;34(9):1114-9.

Schöllhorn L, Bock F, Cursiefen C. Thrombospondin-1 as a Regulator of Corneal Inflammation and Lymphangiogenesis: Effects on Dry Eye Disease and Corneal Graft Immunology. J Ocul Pharmacol Ther. 2015 Sep;31(7):376-85.

Refaian N, Schlereth SL, Koch KR, Notara M, Hos D, Mescher M, Iden S, Bosch JJ, Jager MJ, Cursiefen C, Heindl LM. Comparing the Hem- and Lymphangiogenic Profile of Conjunctival and Uveal Melanoma Cell Lines. Invest Ophthalmol Vis Sci. 2015 Aug 1;56(9):5691-5697.

Breukink MB, Schellevis RL, Boon CJ, Fauser S, Hoyng CB, den Hollander AI, de Jong EK. Genomic Copy Number Variations of the Complement Component C4B Gene Are Associated With Chronic Central Serous Chorioretinopathy. Invest Ophthalmol Vis Sci. 2015 Aug 1;56(9):5608-13.

Kaser-Eichberger A, Schrödl F, Trost A, Strohmaier C, Bogner B, Runge C, Motloch K, Bruckner D, Laimer M, Schlereth SL, Heindl LM, Reitsamer HA. Topography of Lymphatic Markers in Human Iris and Ciliary Body. Invest Ophthalmol Vis Sci. 2015 Jul;56(8):4943-53.

Engel LA, Wittig S, Bock F, Sauerbier L, Scheid C, Holtick U, Chemnitz JM, Hallek M, Cursiefen C, Steven P. Meibography and meibomian gland measurements in ocular graft-versus-host disease. Bone Marrow Transplant. 2015 Jul;50(7):961-7.

Regenfuß B, Dreisow ML, Hos D, Masli S, Bock F, Cursiefen C. The Naïve Murine Cornea as a Model System to Identify Novel Endogenous Regulators of Lymphangiogenesis: TRAIL and rtPA. Lymphat Res Biol. 2015 Jun;13(2):76-84.

Bucher F, Hos D, Müller-Schwefe S, Steven P, Cursiefen C, Heindl LM. Spontaneous long-term course of persistent peripheral graft detachments after Descemet’s membrane endothelial keratoplasty. Br J Ophthalmol. 2015 Jun;99(6):768-72.

Grassmann F, Friedrich U, Fauser S, Schick T, Milenkovic A, Schulz HL, von Strachwitz CN, Bettecken T, Lichtner P, Meitinger T, Arend N, Wolf A, Haritoglou C, Rudolph G, Chakravarthy U, Silvestri G, McKay GJ, Freitag-Wolf S, Krawczak M, Smith RT, Merriam JC, Merriam JE, Allikmets R, Heid IM, Weber BH. A Candidate Gene Association Study Identifies DAPL1 as a Female-Specific Susceptibility Locus for Age-Related Macular Degeneration (AMD). Neuromolecular Med. 2015 Jun;17(2):111-20.

Gehlsen U, Szaszák M, Gebert A, Koop N, Hüttmann G, Steven P. Non-Invasive Multi-Dimensional Two-Photon Microscopy enables optical fingerprinting (TPOF) of immune cells. J Biophotonics. 2015 Jun;8(6):466-79.

Lee HS, Hos D, Blanco T, Bock F, Reyes NJ, Mathew R, Cursiefen C, Dana R, Saban DR. Involvement of corneal lymphangiogenesis in a mouse model of allergic eye disease. Invest Ophthalmol Vis Sci. 2015 May;56(5):3140-8.

Aslanidis A, Karlstetter M, Scholz R, Fauser S, Neumann H, Fried C, Pietsch M, Langmann T. Activated microglia/macrophage whey acidic protein (AMWAP) inhibits NFκB signaling and induces a neuroprotective phenotype in microglia. J Neuroinflammation. 2015 Apr 19;12:77.

Matthaei M, Gillessen J, Muether PS, Hoerster R, Bachmann BO, Hueber A, Cursiefen C, Heindl LM. Epithelial-Mesenchymal Transition (EMT)-Related Cytokines in the Aqueous Humor of Phakic and Pseudophakic Fuchs’ Dystrophy Eyes. Invest Ophthalmol Vis Sci. 2015 Apr;56(4):2749-54.

Bucher F, Fricke J, Cursiefen C, Heindl LM. Trigeminal involvement in parry-romberg syndrome: an in vivo confocal microscopy study of the cornea. Cornea. 2015 Apr;34(4):e10-1.

Tappeiner C, Miserocchi E, Bodaghi B, Kotaniemi K, Mackensen F, Gerloni V, Quartier P, Lutz T, Heiligenhaus A. Abatacept in the treatment of severe, longstanding, and refractory uveitis associated with juvenile idiopathic arthritis. J Rheumatol. 2015 Apr;42(4):706-11.

Enders P, Muether PS, Hermann M, Ristau T, Fauser S. Long-term alterations of systemic vascular endothelial growth factor levels in patients treated with ranibizumab for age-related macular degeneration. Retina. 2015 Mar;35(3):454-8.

Grajewski RS, Caramoy A, Frank KF, Rubbert-Roth A, Fätkenheuer G, Kirchhof B, Cursiefen C, Heindl LM. Spectrum of Uveitis in A German Tertiary Center: Review of 474 Consecutive Patients. Ocul Immunol Inflamm. 2015 Mar 11:1-7.

Karlstetter M, Scholz R, Rutar M, Wong WT, Provis JM, Langmann T. Retinal microglia: just bystander or target for therapy? Prog Retin Eye Res. 2015 Mar;45:30-57.

Hos D, Schlereth SL, Bock F, Heindl LM, Cursiefen C. Antilymphangiogenic therapy to promote transplant survival and to reduce cancer metastasis: what can we learn from the eye? Semin Cell Dev Biol. 2015 Feb;38:117-30.

Ding X, Lucas T, Marcuzzi GP, Pfister H, Eming SA. Distinct functions of epidermal and myeloid-derived VEGF-A in skin tumorigenesis mediated by HPV8. Cancer Res. 2015 Jan 15;75(2):330-43.

Before 2015

Bock F, Matthaei M, Reinhard T, Böhringer D, Christoph J, Ganslandt T, Cursiefen C (2014). High-dose subconjunctival cyclosporine a implants do not affect corneal neovascularization after high-risk keratoplasty. Ophthalmology. Sep;121(9):1677-82.

Lipp M, Bucher F, Parthasarathy A, Hos D, Onderka J, Cursiefen C, Bock F (2014). Blockade of the VEGF isoforms in inflammatory corneal hemangiogenesis andlymphangiogenesis. Graefes Arch Clin Exp Ophthalmol. Jun;252(6):943-9.

Bucher F, Parthasarathy A, Bergua A, Onderka J, Regenfuss B, Cursiefen C, Bock F (2014). Topical Ranibizumab inhibits inflammatory corneal hem- and lymphangiogenesis. Acta Ophthalmol. Mar;92(2):143-8.

Bucher F, Bi Y, Gehlsen U, Hos D, Cursiefen C, Bock F (2014). Regression of mature lymphatic vessels in the cornea by photodynamic therapy. Br J Ophthalmol. Mar;98(3):391-5.

Ristau T, Ersoy L, Lechanteur Y, den Hollander AI, Daha MR, Hahn M, Hoyng CB, Fauser S (2014) Allergy is a protective factor against age-related macular degeneration. Invest Ophthalmol Vis Sci. 55:210-4.

Karlstetter M, Sorusch N, Caramoy A, Dannhausen K, Aslanidis A, Fauser S, Boesl MR, Nagel-Wolfrum K, Tamm ER, Jägle H, Stoehr H, Wolfrum U, Langmann T (2014) Disruption of the retinitis pigmentosa 28 gene Fam161a in mice affects photoreceptor ciliary structure and leads to progressive retinal degeneration. Hum Mol Genet. 23(19):5197-210

Karlstetter M, Nothdurfter C, Aslanidis A, Moeller K, Horn F, Scholz R, Neumann H, Weber BH, Rupprecht R, Langmann T. Translocator protein (18 kDa) (TSPO) is expressed in reactive retinal microglia and modulates microglial inflammation and phagocytosis. J Neuroinflammation 2014 Jan 8;11:3.

Ristau T, Paun C, Ersoy L, Hahn M, Lechanteur Y, Hoyng C, de Jong EK, Daha MR, Kirchhof B, den Hollander AI, Fauser S (2014) Impact of the common genetic associations of age-related macular degeneration upon systemic complement component C3d levels. PLoS One 9(3):e93459.

Cursiefen C, Viaud E, Bock F, Geudelin B, Ferry A, Kadlecová P, Lévy M, Al Mahmood S, Colin S, Thorin E, Majo F, Frueh B, Wilhelm F, Meyer-Ter-Vehn T, Geerling G, Böhringer D, Reinhard T, Meller D, Pleyer U, Bachmann B, Seitz B (2014) Aganirsen antisense oligonucleotide eye drops inhibit keratitis-induced corneal neovascularization and reduce need for transplantation: the I-CAN study. Ophthalmology 121(9):1683-92.

Willenborg S, Eckes B, Brinckmann J, Krieg T, Waisman A, Hartman K, Roers A, Eming SA (2014) Genetic ablation of mast cells redefines the role of mast cells in skin wound healing and bleomycin-induced fibrosis. J Invest Dermatol 134:2005-2015.

Koch KR, Refaian N, Hos D, Schlereth SL, Bosch JJ, Cursiefen C, Heindl LM (2014) Autocrine impact of VEGF-A on uveal melanoma cells. Invest Ophthalmol Vis Sci 55:2697-2704.

Schlereth SL, Neuser B, Caramoy A, Grajewski RS, Koch KR, Schrödl F, Cursiefen C, Heindl LM (2014) Enrichment of lymphatic vessel endothelial hyaluronan receptor 1 (LYVE1)-positive macrophages around blood vessels in the normal human sclera. Invest Ophthalmol Vis Sci. 55(2):865-72.

Busch M, Bauer D, Hennig M, Wasmuth S, Thanos S, Heiligenhaus A (2013) Effects of systemic and intravitreal TNF-a inhibition in experimental autoimmune uveoretinitiis. Invest Ophthalmol Vis Sci 54: 39-46.

Helgason H, Sulem P, Duvvari MR, Luo H, Thorleifsson G, Stefansson H, Jonsdottir I, Masson G, Gudbjartsson DF, Walters GB, Magnusson OT, Kong A, Rafnar T, Kiemeney LA, Schoenmaker-Koller FE, Zhao L, Boon CJ, Song Y, Fauser S, Pei M, Ristau T, Patel S, Liakopoulos S, van de Ven JP, Hoyng CB, Ferreyra H, Duan Y, Bernstein PS, Geirsdottir A, Helgadottir G, Stefansson E, den Hollander AI, Zhang K, Jonasson F, Sigurdsson H, Thorsteinsdottir U, Stefansson K (2013) A rare nonsynonymous sequence variant in C3 is associated with high risk of age-related macular degeneration. Nat Genet. 45:1371-4.

van de Ven JP, Nilsson SC, Tan PL, Buitendijk GH, Ristau T, Mohlin FC, Nabuurs SB, Schoenmaker-Koller FE, Smailhodzic D, Campochiaro PA, Zack DJ, Duvvari MR, Bakker B, Paun CC, Boon CJ, Uitterlinden AG, Liakopoulos S, Klevering BJ, Fauser S, Daha MR, Katsanis N, Klaver CC, Blom AM, Hoyng CB, den Hollander AI (2013) A functional variant in the CFI gene confers a high risk of age-related macular degeneration. Nat Genet. 45:813-7.

Traub S, Morgner J, Martino MM, Höning S, Swartz MA, Wickström SA, Hubbell JA, Eming SA (2013) The promotion of endothelial cell attachment and spreading using FNIII10 fused to VEGF-A165. Biomaterials 34:5958-68.

Hoffmann DC, Willenborg S, Koch M, Zwolanek D, Müller S, Becker AK, Metzger S, Ehrbar M, Kurschat P, Hellmich M, Hubbell JA, Eming SA (2013) Proteolytic processing regulates placental growth factor activities. J Biol Chem 288:17976-89.

Hos D, Koch KR, Bucher F, Bock F, Cursiefen C, Heindl LM (2013) Serum eyedrops antagonize the anti(lymph)angiogenic effects of bevacizumab in vitro and in vivo. Invest Ophthalmol Vis Sci 54:6133-42.

Contreras-Ruiz L, Regenfuss B, Mir FA, Kearns J, Masli S (2013) Conjunctival inflammation in thrombospondin-1 deficient mouse model of Sjogren’s syndrome. PLoS One 8(9): e75937.

Bock F, Maruyama K, Regenfuss B, Hos D, Steven P, Heindl LM, Cursiefen C (2013) Novel anti(lymph)angiogenic treatment strategies for corneal and ocular surface diseases. Prog Retin Eye Res 34: 89-124.

Platonova N, Miquel G, Regenfuss B, Taouji S, Cursiefen C, Chevet E, Bikfalvi A (2013) Evidence for the interaction of fibroblast growth factor-2 with the lymphatic endothelial cell marker LYVE-1. Blood 1217: 1229-1237.

Siebelmann S, Gehlsen U, Hüttmann G, Koop N, Bölke T, Gebert A, Stern ME, Niederkorn JY, Steven P (2013) Development, alteration and real time dynamics of conjunctiva-associated lymphoid tissue. PLoS One. 8:e82355.

Steven P, Le Blanc C, Velten K, Lankenau E, Krug M, Oelckers S, Heindl LM, Gehlsen U, Hüttmann G, Cursiefen C (2013) Optimizing descemet membrane endothelial keratoplasty using intraoperative optical coherence tomography. JAMA Ophthalmol. 131:1135-42.

Bock F, Rössner S, Onderka J, Lechmann M, Pallotta MT, Fallarino F, Boon L, Nicolette C, DeBenedette MA, Tcherepanova IY, Grohmann U, Steinkasserer A, Cursiefen C, Zinser E (2013) Topical application of soluble CD83 induces IDO-mediated immune modulation, increases Foxp3+ T cells, and prolongs allogeneic corneal graft survival. J Immunol. 191(4):1965-75

Grajewski RS, Li J, Wasmuth S, Hennig M, Bauer D, Heiligenhaus A (2012) Intravitreal treatment with antisense oligonucleotides targeting tumor necrosis factor alpha in murine herpes simplex virus type 1 retinitis. Graefes Arch Clin Exp Ophthalmol 250 (2): 231-8.

Hennig M, Bauer D, Wasmuth S, Busch M, Walscheid K, Thanos S, Heiligenhaus A (2012) Everolimus improves experimental autoimmune uveoretinitis. Exp Eye Res 105: 43-52.

Willenborg S, Lucas T, van Loo G, Knipper JA, Krieg T, Haase I, Brachvogel B, Hammerschmidt M, Nagy A, Ferrara N, Pasparakis M, Eming SA (2012) CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair. Blood 120: 613-25.

Gary R, Voelkl S, Palmisano R, Ullrich E, Bosch JJ, Mackensen A (2012) Antigen-specific transfer of functional programmed death ligand 1 from human APCs onto CD8+ T cells via trogocytosis. J Immunol. 188(2):744-52.

Bosch JJ (2012) Immunotherapy of uveal melanoma. Dev Ophthalmol. 49:137-49.

Gehlsen U, Oetke A, Szaszák M, Koop N, Paulsen F, Gebert A, Huettmann G, Steven P (2012) Two-photon fluorescence lifetime imaging monitors metabolic changes during wound healing of corneal epithelial cells in vitro. Graefes Arch Clin Exp Ophthalmol. 250:1293-302.

Rauch A, Wieczorek D, Graf E, Wieland T, Endele S, Schwarzmayr T, Albrecht B, Bartholdi D, Beygo J, Di Donato N, Dufke A, Cremer K, Hempel M, Horn D, Hoyer J, Joset P, Ropke A, Moog U, Riess A, Thiel CT, Tzschach A, Wiesener A, Wohlleber E, Zweier C, Ekici AB, Zink AM, Rump A, Meisinger C, Grallert H, Sticht H, Schenck A, Engels H, Rappold G, Schrock E, Wieacker P, Riess O, Meitinger T, Reis A*, Strom TM* (2012) Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study. Lancet 380: 1674-82.

Hoyer J, Ekici AB, Endele S, Popp B, Zweier C, Wiesener A, Wohlleber E, Dufke A, Rossier E, Petsch C, Zweier M, Gohring I, Zink AM, Rappold G, Schrock E, Wieczorek D, Riess O, Engels H, Rauch A, Reis A (2012) Haploinsufficiency of ARID1B, a member of the SWI/SNF-a chromatin-remodeling complex, is a frequent cause of intellectual disability. Am J Hum Genet 90: 565-72.

Vierkotten S, Muether PS, Fauser S (2011) Overexpression of HTRA1 leads to ultrastructural changes in the elastic layer of Bruch’s membrane via cleavage of extracellular matrix components. PLoS One 6:e22959.

Hos D, Regenfuss B, Bock F, Onderka J, Cursiefen C (2011) Blockade of insulin receptor substrate-1 inhibits corneal lymphangiogenesis. Invest Ophthalmol Vis Sci 52:5778-85.

Hos D, Saban DR, Bock F, Regenfuss B, Onderka J, Masli S, Cursiefen C (2011) Suppression of inflammatory corneal lymphangiogenesis by application of topical corticosteroids. Arch Ophthalmol 129:445-52.

Heindl LM, Hofmann-Rummelt C, Adler W, Bosch JJ, Holbach LM, Naumann GO, Kruse FE, Cursiefen C (2011) Prognostic significance of tumor-associated lymphangiogenesis in malignant melanomas of the conjunctiva. Ophthalmology 118:2351-2360.

Haile ST*, Bosch JJ*, Agu NI, Zeender AM, Somasundaram P, Srivastava MK, Britting S, Wolf JB, Ksander BR, Ostrand-Rosenberg S (2011) Tumor cell programmed death ligand 1-mediated T cell suppression is overcome by coexpression of CD80. J Immunol. 186:6822-9. *these authors contributed equally

Abou Jamra R, Philippe O, Raas-Rothschild A, Eck SH, Graf E, Buchert R, Borck G, Ekici A, Brockschmidt FF, Nothen MM, Munnich A, Strom TM, Reis A, Colleaux L (2011) Adaptor protein complex 4 deficiency causes severe autosomal-recessive intellectual disability, progressive spastic paraplegia, shy character, and short stature. Am J Hum Genet 88: 788-95.

Cursiefen C, Maruyama K, Bock F, Saban D, Sadrai Z, Lawler J, Dana R, Masli S (2011) Thrombospondin 1 inhibits inflammatory lymphangiogenesis by CD36 ligation on monocytes. J Exp Med 208(5):1083-92

Steven P, Bock F, Hüttmann G, Cursiefen C (2011) Intravital two-photon microscopy of immune cell dynamics in corneal lymphatic vessels. PLoS One. 6:e26253.

Karlstetter M, Walczak Y, Weigelt K, Ebert S, Van den Brulle J, Schwer H, Fuchshofer R, Langmann T (2010) The novel activated microglia/macrophage WAP domain protein, AMWAP, acts as a counter-regulator of proinflammatory response. J Immunol 185:3379-3390.

Langmann T, Di Gioia SA, Rau I, Stohr H, Maksimovic NS, Corbo JC, Renner AB, Zrenner E, Kumaramanickavel G, Karlstetter M, Arsenijevic Y, Weber BH, Gal A, Rivolta C (2010) Nonsense mutations in FAM161A cause RP28-associated recessive retinitis pigmentosa. Am J Hum Genet 87:376-381.

Corbo JC, Lawrence KA, Karlstetter M, Myers CA, Abdelaziz M, Dirkes W, Weigelt K, Seifert M, Benes V, Fritsche LG, Weber BH, Langmann T (2010) CRX ChIP-seq reveals the cis-regulatory architecture of mouse photoreceptors. Genome Res 20:1512-1525.

Lucas T, Waisman A, Ranjan R, Roes J, Krieg T, Müller W, Roers A, Eming SA (2010) Differential roles of macrophages in diverse phases of skin repair. Journal of Immunology 184: 3964-77.

Heindl LM, Hofmann TN, Adler W, Knorr HL, Holbach LM, Naumann GO, Kruse FE, Cursiefen C (2010) Intraocular tumor-associated lymphangiogenesis: a novel prognostic factor for ciliary body melanomas with extraocular extension? Ophthalmology 117:334-342.

Heindl LM, Hofmann-Rummelt C, Adler W, Holbach LM, Naumann GO, Kruse FE, Cursiefen C (2010) Tumor-associated lymphangiogenesis in the development of conjunctival squamous cell carcinoma. Ophthalmology 117:649-658.

Bosch JJ, Iheagwara UK, Reid S, Srivastava MK, Wolf J, Lotem M, Ksander BR, Ostrand-Rosenberg S (2010) Uveal melanoma cell-based vaccines express MHC II molecules that traffic via the endocytic and secretory pathways and activate CD8(+) cytotoxic, tumor-specific T cells. Cancer Immunol Immunother. 59:103-12.

Dietrich T*, Bock F*, Yuen D, Hos D, Bachmann BO, Zahn G, Wiegand S, Chen L, Cursiefen C (2010) Cutting edge: lymphatic vessels, not blood vessels, primarily mediate immune rejections after transplantation. J Immunol 184(2):535-9 *contributed equally

Regenfuss B, Onderka J, Bock F, Hos D, Maruyama K, Cursiefen C (2010) Genetic heterogeneity of lymphangiogenesis in different mouse strains. Am J Pathol 1771: 501-510.

Huffmeier U, Uebe S, Ekici AB, Bowes J, Giardina E, Korendowych E, Juneblad K, Apel M, McManus R, Ho P, Bruce IN, Ryan AW, Behrens F, Lascorz J, Bohm B, Traupe H, Lohmann J, Gieger C, Wichmann HE, Herold C, Steffens M, Klareskog L, Wienker TF, Fitzgerald O, Alenius GM, McHugh NJ, Novelli G, Burkhardt H, Barton A, Reis A (2010) Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis. Nat Genet 42: 996-9.

Bauer D, Wasmuth S, Hennig M, Baehler H, Steuhl KP, and Heiligenhaus A (2009) Amniotic membrane transplantation induces apoptosis in T lymphocytes in murine corneas with experimental herpetic stromal keratitis. Invest Ophthalmol Vis Sci 50:3188-3198.

Grajewski RS, Hansen AM, Agarwal RK, Kronenberg M, Sidobre S, Su SB, Silver PB, Tsuji M, Franck RW, Lawton AP, Chan CC, Caspi RR. Activation of invariant NKT cells ameliorates experimental ocular autoimmunity by a mechanism involving innate IFN-gamma production and dampening of the adaptive Th1 and Th17 responses. (2008) J Immunol. Oct 1;181(7):4791-7.

Hos D, Bock F, Dietrich T, Onderka J, Kruse FE, Thierauch KH, Cursiefen C (2008) Inflammatory corneal (lymph)angiogenesis is blocked by VEGFR-tyrosine kinase inhibitor ZK 261991, resulting in improved graft survival after corneal transplantation. Invest Ophthalmol Vis Sci 49:1836-42.

Hos D, Bachmann B, Bock F, Onderka J, Cursiefen C (2008) Age-related changes in murine limbal lymphatic vessels and corneal lymphangiogenesis. Exp Eye Res 87:427-32.

Regenfuss B, Bock F, Parthasarathy A, Cursiefen C (2008) Corneal (lymph)angiogenesis–from bedside to bench and back: a tribute to Judah Folkman. Lymphat Res Biol. 6:191-201.

Rauch A, Thiel CT, Schindler D, Wick U, Crow YJ, Ekici AB, van Essen AJ, Goecke TO, Al-Gazali L, Chrzanowska KH, Zweier C, Brunner HG, Becker K, Curry CJ, Dallapiccola B, Devriendt K, Dörfler A, Kinning E, Megarbane A, Meinecke P, Semple RK, Spranger S, Toutain A, Trembath RC, Voß E, Wilson L, Hennekam R, de Zegher F, Dörr HG, Reis A. (2008) Mutations in the Pericentrin (PCNT) Gene Cause Primordial Dwarfism. Science 319: 816-819.

Steven P, Rupp J, Hüttmann G, Koop N, Lensing C, Laqua H, Gebert A (2008) Experimental induction and three-dimensional two-photon imaging of conjunctiva-associated lymphoid tissue. Invest Ophthalmol Vis Sci. 49:1512-7.

Heiligenhaus A, Niewerth M, Ganser G, Heinz C, Minden K, German Uveitis in Childhood Study Group (2007) Prevalence and complications of uveitis in juvenile idiopathic arthritis in a population-based nation-wide study in Germany: suggested modification of the current screening guidelines. Rheumatology 46: 1015-1019.

Bosch JJ, Thompson JA, Srivastava MK, Iheagwara UK, Murray TG, Lotem M, Ksander BR, Ostrand-Rosenberg S (2007) MHC class II-transduced tumor cells originating in the immune-privileged eye prime and boost CD4(+) T lymphocytes that cross-react with primary and metastatic uveal melanoma cells. Cancer Res. 67:4499-506.

Grajewski RS, Silver PB, Agarwal RK, Su SB, Chan CC, Liou GI and Caspi RR (2006) Endogenous expression of IRBP can be dispensable for generation of natural CD4+CD25+ regulatory T cells that protect from IRBP-induced retinal autoimmunity. J Exp Med. 203(4): 851-56.

Heiligenhaus A, Li HF, Yang Y, Wasmuth S, Steuhl KP, Bauer D (2005) Transplantation of amniotic membrane in murine herpes stromal keratitis modulates matrix metalloproteinases in the cornea. Invest Ophthalmol Vis Sci 46: 4079-4085

Cursiefen C, Chen L, Borges LP, Jackson D, Cao J, Radziejewski C, D’Amore PA, Dana MR, Wiegand SJ, Streilein JW (2004) VEGF-A stimulates lymphangiogenesis and hemangiogenesis in inflammatory neovascularization via macrophage recruitment. J Clin Invest. 113:1040-50.

Avichezer D, Grajewski RS, Chan CC, Mattapallil MJ, Silver PB, Raber JA, Liou GI, Wiggert B, Lewis GM, Donoso LA, Caspi RR (2003) An immunologically privileged retinal antigen elicits tolerance: major role for central selection mechanisms. J Exp Med. 198(11): 1665-76.