Research Groups

There are seven regular research groups (projects) in research unit FOR 2240 led by one or two principal investigators. The projects of first-time applicants also have one or two non-funded co-applicants with status as senior researchers as part of the leadership team. Working in the groups at the post-doc level are several clinician-scientists, many on research rotation posts (“Gerok”). Other group members are funded in a variety of ways, including DFG-financed positions. There is a growing number of PhD students, the majority of them female, guest scientists, and interns that the research unit has attracted. The laboratory work of the entire research unit FOR 2240 is considerably aided by teams of medical technical assistants, some DFG-funded as well. Most members of the research groups are located in Cologne, with two teams in Erlangen-Nürnberg and now in the second funding period, also support from Co-Applicants in Lübeck and Berlin.

Project P1 Lymph-Transplant

Induction of corneal transplant tolerance by anti(lymph)angiogenic therapy

Project P2 Modulators of LA

Identification of novel endogenous modulators of developmental and inflammatory lymphangiogenesis by analyzing mouse strain-specific differences

Project N1 Ocular GvHD

Lymph- and hemangiogenesis in ocular graft-versus-host disease

Project N2 ABCB5 & Pterygium

The role of ABCB5-expressing limbal epithelial stem cells in corneal lymphangiogenic privilege and pterygium pathogenesis

Project P4 Ocular Melanoma

The role of midkine in tumor-associated lymphangiogenesis and metastasis of ocular malignant melanoma

Project P5 Myeloid Cells

Myeloid cell function in corneal hem- and lymphangiogenesis

Project P6 Microglia in AMD

Role of complement receptors and microglia in age-related macular degeneration

Project P8 Uveitis (2015-2018)

The role of interleukin (IL)-10 in the pathogenesis of autoimmune uveitis in mice and man