Dr. rer. nat. Karina Hadrian

Scientific career

2023- Project leader (together with Prof. Cursiefen and PD Dr. Hos) Center for Molecular Medicine Cologne (CMMC) University of Cologne

2019- PostDoc in Project 5 “Myeloid cell function in corneal hem- and lymphangiogenesis” in the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Department of Ophthalmology, University of Cologne

2016-2020 Dissertation (Dr. rer. nat.) Biology, University of Duisburg-Essen, Essen University Hospital, Department of Ophthalmology,Supervisor: PD Dr. med. Michael Böhm, “Topographic differential analysis and function of age-related protein expression in the RPE of Callithrix jacchus”

2010-2013 Biochemistry – Ruhr-University Bochum, Bachelor of Science, Supervisor: Prof. Dr. Albrecht Bufe, Department of Experimental Pneumology

2013-2015 Biochemistry – Ruhr-University Bochum, Master of Science, Supervisor: Prof. Dr. Wolfgang Linke, Department of Cardiovascular Physiology

Prizes and awards

2022 Member of the board team of the DOG division “youngDOG”
2020 Sicca advancement award for research of dry eye disease
2010 Leonardo da Vinci Grant for Internships in the EU Cancer Research Institute, Cambridge, UK
2009 Leonardo da Vinci Grant for Internships in the EU John Innes Centre, Norwich, UK

Selected publications

Hadrian K, Musial M, Schönberg A, Georgiev T, Küper C, Bock F, Jantsch J, Cursiefen C, Eming SA, Hos D (2022) The Role of the Osmosensitive Transcription Factor NFAT5 in Corneal Edema Resorption after Injury. Exp Mol Med. doi:10.1038/s12276-023-00954-w (2023)

Volatier T, Schumacher B, Meshko B, Hadrian K, Cursiefen C, Notara M. (2023) Short-Term UVB Irradiation Leads to Persistent DNA Damage in Limbal Epithelial Stem Cells, Partially Reversed by DNA Repairing Enzymes. Biology

Clahsen T, Hadrian K, Notara M,[…], Kashkar H, […], Cursiefen C. (2022) The novel role of lymphatic vessel in the pathogenesis of ocular diseases. Prog Retin Eye Res.

Zhang W, Schönberg A, Basset F, Hadrian K, Hos D, Becker M, Bock F, Cursiefen C. (2022) Different Murine High-Risk Corneal Transplant Settings Vary Significantly in Their (Lymph)angiogenic and Inflammatory Cell Signatures. Invest Ophthalmol Vis Sci

Hadrian K, Willenborg S, Bock F, Cursiefen C, Eming SA, Hos D. Macrophage-Mediated Tissue Vascularization: Similarities and Differences Between Cornea and Skin. Front Immunol (2021) 12:667830.

Hadrian K, Melkonyan H, Schlatt S, Wistuba J, Wasmuth S, Heiligenhaus A, Thanos S, Böhm MRR. Age-related distribution and potential role of SNCB in topographically different retinal areas of the common marmoset Callithrix jacchus, including the macula. Exp Eye Res (2019) 185:107676

König S, Hadrian K, Schlatt S, Wistuba J, Thanos S, Böhm MRR. Topographic protein profiling of the age-related proteome in the retinal pigment epithelium of Callithrix jacchus with respect to macular degeneration. J Proteomics, (2019)191:1-15.

Böhm MRR, Hadrian K, Brockhaus K, Melkonyan H, Thanos S. Age-Related Expression of Beta-Synuclein in the Ascending Visual Pathway and Comparative Analysis of its Function within the Neuroretina and Cerebral Cortex in-vitro. J Alzheimers Dis Parkinsonism,(2018) 8(1): 427