Curriculum Vitae

Univ.-Prof. Dr. med. Ludwig Maximilian Heindl

Ludwig Heindl

Department of Ophthalmology
University of Cologne
Kerperner Str. 62
50937 Cologne, GERMANY
Tel. (+49)-221-478 4300
Fax. (+49)-221-478 5094

Scientific career

1998-2006 Study of Medicine at the Universities of Erlangen-Nuremberg/Germany and Vienna/Austria, Medical Licensure

2006 Doctorate degree (Dr. med.), (magna cum laude) at the University of Erlangen-Nuremberg

2006-2010 Residency, Department of Ophthalmology, University of Erlangen-Nuremberg

2006-2010 Training in Ophthalmic Pathology, Prof. Dr. G.O.H. Naumann, University of Erlangen-Nuremberg

2011 Specialist Certification in Ophthalmology

2011- Consultant in General Ophthalmology, Ophthalmic Oncology and Ophthalmic Pathology, Department of Ophthalmology, University of Cologne

2012 Habilitation and Venia Legendi at the Faculty of Medicine, University of Cologne

2013- Head of Ophthalmic Oncology, Ophthalmic Plastic and Reconstructive Service, Department of Ophthalmology, University of Cologne

2015- Principal Investigator of Project 4 “Tumor-associated lymphangiogenesis and its inhibition as a novel therapeutic strategy in conjunctival melanomas” in the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Department of Ophthalmology, University of Cologne

2016- University Professor (W2) for Ophthalmic Oncology, University of Cologne

2016- Member of the Executive Board, Center for Integrated Oncology (CIO) Cologne-Bonn

2018- Principal Investigator of Project P4 “The role of midkine in tumor-associated lymphangiogenesis and metastasis of ocular malignant melanoma” in the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Department of Ophthalmology, University of Cologne

Prizes and honors

2007 Junior Award – European Society of Ophthalmic Plastic and Reconstructive Surgery (ESOPRS)

2008 Best Paper Award – American Academy of Ophthalmology (AAO)

2010 Senator-Hermann-Wacker-Award – German Ophthalmological Society (DOG)

2011 Best Young Investigator Award – European Ophthalmic Oncology Group (OOG)

2011 Editor’s Choice Award – American Academy of Ophthalmology (AAO)

2012 Novartis Travel Fellowship – International Society for Eye Research (ISER)

2012 Ludwig von Sallmann Clinician-Scientist Award – Association for Research in Vision and Ophthalmology (ARVO)

Selected publications

Matthaei M, Sandhaeger H, Hermel M, Adler W, Jun AS, Cursiefen C, Heindl LM. Changing Indications in Penetrating Keratoplasty: A Systematic Review of 34 Years of Global Reporting. Transplantation. 2017 Jun;101(6):1387-1399.

Grajewski RS, Barahmand Pour N, Burian K, Caramoy A, Kirchhof B, Cursiefen C, Heindl LM. Analysis of the impact of allergy and atopy on new onset of uveitis. Acta Ophthalmol. 2017 May;95(3):e236-e241.

Bosch JJ, Heindl LM. [Novel Adjuvant Therapy for Ocular Melanoma]. Klin Monbl Augenheilkd. 2017 May;234(5):670-673.

Cursiefen C, Bock F, Clahsen T, Regenfuss B, Reis A, Steven P, Heindl LM, Bosch JJ, Hos D, Eming S, Grajewski R, Heiligenhaus A, Fauser S, Austin J, Langmann T. [New Therapeutic Approaches in Inflammatory Diseases of the Eye – Targeting Lymphangiogenesis and Cellular Immunity: Research Unit FOR 2240 Presents Itself]. Klin Monbl Augenheilkd. 2017 May;234(5):679-685.

Schaub F, Enders P, Bachmann BO, Heindl LM, Cursiefen C. Effect of corneal collagen crosslinking on subsequent deep anterior lamellar keratoplasty (DALK) in keratoconus. Graefes Arch Clin Exp Ophthalmol. 2017 Apr;255(4):811-816.

Heindl LM, Koch KR, Hermann MM, Merkelbach-Bruse S, Schultheis AM, Wagener S, Büttner R, Mauch C, Schuler-Thurner B, Schuler G, Cursiefen C. Block Excision of Iridociliary Tumors Enables Molecular Profiling and Immune Vaccination. Ophthalmology. 2017 Feb;124(2):268-270.

Grajewski RS, Heindl LM. Macular thickening of uveitic eyes in the absence of macular oedema and epiretinal membranes. Acta Ophthalmol. 2017 Feb;95(1):e77-e78.

Hoerster R, Schlaak M, Koch KR, Ortmann M, Mauch C, Heindl LM. [Merkel cell carcinoma of the eyelid. An often unrecognized tumor entity : Clinical aspects and treatment strategies]. Ophthalmologe. 2017 Feb;114(2):134-139.

Grajewski RS, Heindl LM. [Masquerades and Trojans: When tumors disguise as uveitis]. Ophthalmologe. 2016 Dec;113(12):1091.

van Setten GB, Trost A, Schrödl F, Kaser-Eichberger A, Bogner B, van Setten M, Heindl LM, Grabner G, Reitsamer HA. Immunohistochemical Detection of CTGF in the Human Eye. Curr Eye Res. 2016 Dec;41(12):1571-1579.

Schaub F, Adler W, Koenig MC, Enders P, Grajewski RS, Cursiefen C, Heindl LM. Impact of allergy and atopy on the risk of pseudophakic cystoid macular edema. Graefes Arch Clin Exp Ophthalmol. 2016 Dec;254(12):2417-2423.

Schaub F, Simons HG, Enders P, Bachmann BO, Roters S, Cursiefen C, Heindl LM. [Corneal donation: Dilemma between growing demand and declining donor rate]. Ophthalmologe. 2016 Dec;113(12):1058-1065.

Bucher F, Fricke J, Neugebauer A, Cursiefen C, Heindl LM. Ophthalmological manifestations of Parry-Romberg syndrome. Surv Ophthalmol. 2016 Nov – Dec;61(6):693-701.

Grajewski RS, Boelke AC, Adler W, Meyer S, Caramoy A, Kirchhof B, Cursiefen C, Heindl LM. Spectral-domain optical coherence tomography findings of the macula in 500 consecutive patients with uveitis. Eye (Lond). 2016 Nov;30(11):1415-1423.

Schaub F, Enders P, Zachewicz J, Heindl LM, Stanzel TP, Cursiefen C, Bachmann BO. Impact of Donor Age on Descemet Membrane Endothelial Keratoplasty Outcome: Evaluation of Donors Aged 17-55 Years. Am J Ophthalmol. 2016 Oct;170:119-127.

Boppudi S, Bögershausen N, Hove HB, Percin EF, Aslan D, Dvorsky R, Kayhan G, Li Y, Cursiefen C, Tantcheva-Poor I, Toft PB, Bartsch O, Lissewski C, Wieland I, Jakubiczka S, Wollnik B, Ahmadian MR, Heindl LM, Zenker M. Specific mosaic KRAS mutations affecting codon 146 cause oculoectodermal syndrome and encephalocraniocutaneous lipomatosis. Clin Genet. 2016 Oct;90(4):334-42.

Schlereth SL, Kremers S, Schrödl F, Cursiefen C, Heindl LM. Characterization of Antigen-Presenting Macrophages and Dendritic Cells in the Healthy Human Sclera. Invest Ophthalmol Vis Sci. 2016 Sep 1;57(11):4878-4885.

Avgitidou G, Koch KR, Fries JW, Cursiefen C, Heindl LM. [Pediatric conjunctival tumor with cilia]. Ophthalmologe. 2016 Sep;113(9):783-5.

Schaub F, Enders P, Cursiefen C, Heindl LM. Split-cornea transplantation – a microbiologically safe approach? Graefes Arch Clin Exp Ophthalmol. 2016 Jul;254(7):1441-2.

Grajewski RS, Koch KR, Koch HR, Ciotu IM, Cursiefen C, Heindl LM. Cataract in pseudohypoparathyroidism. J Cataract Refract Surg. 2016 Jul;42(7):1094-6.

Koch KR, Heindl LM. Axenfeld Loop vs Extrasclerally Extending Ciliary Body Tumor-Reply. JAMA Ophthalmol. 2016 Jul 1;134(7):846.

Khatib R, Göbel H, Kurschat C, Röcken C, Cursiefen C, Steven P, Heindl LM. [Refractory pseudofollicular conjunctivitis]. Ophthalmologe. 2016 Jul;113(7):612-4.

Hos D, Bucher F, Regenfuss B, Dreisow ML, Bock F, Heindl LM, Eming SA, Cursiefen C. IL-10 Indirectly Regulates Corneal Lymphangiogenesis and Resolution of Inflammation via Macrophages. Am J Pathol. 2016 Jan;186(1):159-71.

Refaian N, Schlereth SL, Koch KR, Notara M, Hos D, Mescher M, Iden S, Bosch JJ, Jager MJ, Cursiefen C, Heindl LM. Comparing the Hem- and Lymphangiogenic Profile of Conjunctival and Uveal Melanoma Cell Lines. Invest Ophthalmol Vis Sci. 2015;56(9):5691-7

Koch KR, Refaian N, Hos D, Schlereth SL, Bosch JJ, Cursiefen C, Heindl LM. Autocrine impact of VEGF-A on uveal melanoma cells. Invest Ophthalmol Vis Sci 2014 ;55:2697-2704.

Hos D, Koch KR, Bucher F, Cursiefen C, Heindl LM. Serum eyedrops antagonize the anti(lymph)angiogenic effects of bevacizumab in vitro and in vivo. Invest Ophthalmol Vis Sci 2013 ;54:6133-6142.

Heindl LM, Hofmann-Rummelt C, Adler W, Bosch JJ, Holbach LM, Naumann GO, Kruse FE, Cursiefen C. Prognostic significance of tumor-associated lymphangiogenesis in malignant melanomas of the conjunctiva. Ophthalmology 2011 ;118:2351-2360.

Heindl LM, Hofmann TN, Adler W, Knorr HL, Holbach LM, Naumann GO, Kruse FE, Cursiefen C.  Intraocular tumor-associated lymphangiogenesis: a novel prognostic factor for ciliary body melanomas with extraocular extension? Ophthalmology 2010 ;117:334-342.

Heindl LM, Hofmann-Rummelt C, Adler W, Holbach LM, Naumann GO, Kruse FE, Cursiefen C. Tumor-associated lymphangiogenesis in the development of conjunctival squamous cell carcinoma. Ophthalmology 2010 ;117:649-658.