1979 – 1986 Medical School at the Universities of Göttingen und Lübeck (Germany)
1986 State Examination and License as Physician (Approbation)
1983 – 1986 Doctorate degree (Dr. med.) at the Medical University of Lübeck
1986 – 1988 Stipend of the DFG and post-doctoral fellow, Institute of Human Genetics, University of Göttingen
1989 – 1998 Hochschulassistent (C1), Institute of Human Genetics, Free University Berlin (later fused with Charité, Humboldt University Berlin)
1990 – 2000 Head of molecular diagnostics laboratory
1995 Habilitation in Human Genetics at Charité, Humboldt University Berlin
1995 – 2000 Founder and project leader, “Microsatellite Centre / Gene Mapping Centre” at Max-Delbrück-Centrum for Molecular Medicine, Berlin
1996 Board Certification for Human Genetics
1998 Ass. Professor (C3) of Medical Genetics and Gene Mapping at Humboldt Univ. Berlin and group leader at the Max-Delbrück-Center (MDC), Berlin
2000 Offer of Chair in Molecular Medicine (C4) at Humboldt Univ. Berlin (declined)
2000- Full Professor of Human Genetics (C4) and Director of the Institute of Human Genetics at the University of Erlangen-Nürnberg
2007- Chairman of the Board, Interdisciplinary Center for Clinical Research (IZFK) of the Medical Faculty of the University of Erlangen-Nürnberg
2011 Offer of the Chair of Human Genetics (W3) at University Göttingen (declined)
2015- Principal Investigator of Project 2 “Identification of novel endogenous modulators of (inflammatory) lymphangiogenesis by analyzing mouse strain-specific differences” in the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Institute of Human Genetics at the University Hospital of Erlangen
-2017 Chairman of the Academic Senate of the University of Erlangen-Nürnberg
2018- Principal Investigator of Project P2 “Identification of novel endogenous modulators of developmental and inflammatory lymphangiogenesis by analyzing mouse strain-specific differences” in the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Institute of Human Genetics at the University Hospital of Erlangen
Prizes and honors
1986 Stipend of the German Research Foundation (DFG)
1994 Scientific Award of the German Society of Human Genetics (GfH)
since 2007 Member, German National Academy of Sciences Leopoldina
2007 – 2011 Corresponding Member
since 2011 Member, Academy of Sciences and Literature Mainz
since 2011 Corresponding Member, Austrian Academy of Sciences
Cursiefen C, Bock F, Clahsen T, Regenfuss B, Reis A, Steven P, Heindl LM, Bosch JJ, Hos D, Eming S, Grajewski R, Heiligenhaus A, Fauser S, Austin J, Langmann T. [New Therapeutic Approaches in Inflammatory Diseases of the Eye – Targeting Lymphangiogenesis and Cellular Immunity: Research Unit FOR 2240 Presents Itself]. Klin Monbl Augenheilkd. 2017 May;234(5):679-685.
Rauch A, Wieczorek D, Graf E, Wieland T, Endele S, Schwarzmayr T, Albrecht B, Bartholdi D, Beygo J, Di Donato N, Dufke A, Cremer K, Hempel M, Horn D, Hoyer J, Joset P, Ropke A, Moog U, Riess A, Thiel CT, Tzschach A, Wiesener A, Wohlleber E, Zweier C, Ekici AB, Zink AM, Rump A, Meisinger C, Grallert H, Sticht H, Schenck A, Engels H, Rappold G, Schrock E, Wieacker P, Riess O, Meitinger T, Reis A*, Strom TM* (2012) Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study. Lancet 380: 1674-82.
Hoyer J, Ekici AB, Endele S, Popp B, Zweier C, Wiesener A, Wohlleber E, Dufke A, Rossier E, Petsch C, Zweier M, Gohring I, Zink AM, Rappold G, Schrock E, Wieczorek D, Riess O, Engels H, Rauch A, Reis A (2012) Haploinsufficiency of ARID1B, a member of the SWI/SNF-a chromatin-remodeling complex, is a frequent cause of intellectual disability. Am J Hum Genet 90: 565-72.
Abou Jamra R, Philippe O, Raas-Rothschild A, Eck SH, Graf E, Buchert R, Borck G, Ekici A, Brockschmidt FF, Nothen MM, Munnich A, Strom TM, Reis A, Colleaux L (2011) Adaptor protein complex 4 deficiency causes severe autosomal-recessive intellectual disability, progressive spastic paraplegia, shy character, and short stature. Am J Hum Genet 88: 788-95.
Huffmeier U, Uebe S, Ekici AB, Bowes J, Giardina E, Korendowych E, Juneblad K, Apel M, McManus R, Ho P, Bruce IN, Ryan AW, Behrens F, Lascorz J, Bohm B, Traupe H, Lohmann J, Gieger C, Wichmann HE, Herold C, Steffens M, Klareskog L, Wienker TF, Fitzgerald O, Alenius GM, McHugh NJ, Novelli G, Burkhardt H, Barton A, Reis A (2010) Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis. Nat Genet 42: 996-9.
Rauch A, Thiel CT, Schindler D, Wick U, Crow YJ, Ekici AB, van Essen AJ, Goecke TO, Al-Gazali L, Chrzanowska KH, Zweier C, Brunner HG, Becker K, Curry CJ, Dallapiccola B, Devriendt K, Dörfler A, Kinning E, Megarbane A, Meinecke P, Semple RK, Spranger S, Toutain A, Trembath RC, Voß E, Wilson L, Hennekam R, de Zegher F, Dörr HG, Reis A. (2008) Mutations in the Pericentrin (PCNT) Gene Cause Primordial Dwarfism. Science 319: 816-819.