Curriculum Vitae
Department of Ophthalmology
Experimental Immunology of the Eye
University of Cologne
Kerpener Straße 62
50937 Cologne, GERMANY
Visitor’s Address:
Building 35 (Anatomy)
Joseph-Stelzmann-Str. 9
50931 Cologne, GERMANY
Scientific career
2015- Affiliated PhD student in Project 6 “Role of the complement system and microglia in age-related macular degeneration” in the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Department of Ophthalmology, University of Cologne
2018- Affiliated PhD student in Project 6 “Role of complement receptors and microglia in age-related macular degeneration” in the DFG Research Unit FOR 2240 “Angiogenesis, Lymphangiogenesis and Cellular Immunity in Inflammatory Diseases of the Eye” at the Department of Ophthalmology, University of Cologne
2020- PostDoc and Lableader, Experimental Immunology of the eye, University of Cologne
2022- Member of the International Society of Eye Research: ISER
2022- Editorial Board, Cellular Neuropathology (Frontiers in Cellular Neuroscience)
Prizes and honors
2018 Pro Retina Travel Award
2019 IPaK Travel Award
2019 Retina Suisse Award
2022 German Research Program for Ophthalmology, Bayer
Selected publications
Tabel, M., Wolf, A., Szczepan, M., Xu, H-, Jagle, H., Moehle, C., Chen, M., Langmann, T. (2022) Genetic targeting or pharmacological inhibition of galectin-3 dampens microglia reactivity and delays retinal degeneration. J Neuroinflammation. 19(1):229
Kinuthia, U. M., Wolf, A., & Langmann, T. (2020). Microglia and Inflammatory Responses in Diabetic Retinopathy. Frontiers in Immunology, 11(2888). doi:10.3389/fimmu.2020.564077
Wolf, A., Herb, M., Schramm, M., & Langmann, T. (2020). The TSPO-NOX1 axis controls phagocyte-triggered pathological angiogenesis in the eye. Nat Commun, 11(1), 2709.
Behnke, V., Wolf, A., & Langmann, T. (2020). The role of lymphocytes and phagocytes in age-related macular degeneration (AMD). Cell Mol Life Sci, 77(5), 781-788.
Wolf, A., & Langmann, T. (2019). Anti-VEGF-A/ANG2 combotherapy limits pathological angiogenesis in the eye: a replication study. EMBO Mol Med, 11(5).
Herb, M., Gluschko, A., Wiegmann, K., Farid, A., Wolf, A., Utermohlen, O., Krug, O., Krönke, M., Schramm, M. (2019). Mitochondrial reactive oxygen species enable proinflammatory signaling through disulfide linkage of NEMO. Sci Signal, 12(568).
Balser, C. and Wolf, A. (first co-authorship), Herb, M., & Langmann, T. (2019). Co-inhibition of PGF and VEGF blocks their expression in mononuclear phagocytes and limits neovascularization and leakage in the murine retina. J Neuroinflammation, 16(1), 26.
Rashid, K., Geissl, L., Wolf, A., Karlstetter, M., & Langmann, T. (2018). Transcriptional regulation of Translocator protein (18kDa) (TSPO) in microglia requires Pu.1, Ap1 and Sp factors. Biochim Biophys Acta Gene Regul Mech, 1861(12), 1119-1133.
Rashid, K., Wolf, A., & Langmann, T. (2018). Microglia Activation and Immunomodulatory Therapies for Retinal Degenerations. Front Cell Neurosci, 12, 176
Wolf, A., Aslanidis, A., & Langmann, T. (2017). Retinal expression and localization of Mef2c support its important role in photoreceptor gene expression. Biochem Biophys Res Commun, 483(1), 346-351.
