Three thematic areas

lymphatic vessels

Lymphatic vessels are an important part of the “afferent” arm of inflammatory and immune responses. Via lymphatic vessels, antigen-presenting cells and antigens from the periphery enter the regional lymph nodes to induce local immune responses.

microglia

Microglia-mediated retinal immune processes are an early occurring pathophysiological hallmark of hereditary retinal dystrophies, age-related macular degeneration, diabetic retinopathy and glaucoma.

macrophages

Macrophages along with resident microglial cells of the retina appear to play a key role in all ocular inflammatory processes to be studied here. Thus, certain polarized phenotypes of macrophages mesh intimately with pathological lymphangiogenesis.

Background and specific aims

Background

The eye is the most important human sensory organ with which we perceive 90 percent of all information in our environment. The optical transparency as well as a structural and functional integrity of the eye is essential for good vision.

Specific aims

The general goal of the FOR 2240 is the concerted investigation of the so far still poorly understood pathogenesis of aberrant immune processes of the eye and the development of innovative new diagnostic and therapeutic concepts.

News

Antonia Howaldt accepted into the Cologne Clinician Scientist Program

We proudly announce that Antonia Howaldt has been accepted into the Clinician Scientist Program of the Medical Faculty of the University of Cologne. Designed for physician-scientists seeking careers that combine research with clinical training, the Cologne Clinician Scientist Program offers a three-year program with protected research time supporting translational research (50% clinical training, 50% research),Continue reading

FOR2240 Scientist Dr. Alexander C. Rokohl was selected for the Cologne Clinician Scientist Program

We are proud to announce that Dr. Alexander C. Rokohl was selected to attend the Cologne Clinician Scientist Program (CCSP) of the Medical Faculty at the University of Cologne. The outstanding scientific achievements of Dr. Alexander C. Rokohl attracted a lot of attention at national and international scientific meetings and he won several scientific awardsContinue reading

Young Cologne Eye Researcher Dr. Karina Hadrian wins Prize of the DOG

The department of ophthalmology at the University Hospital of Cologne is very proud to announce that Dr. Karina Hadrian won the Sicca advancement award for research of the dry eye and surface disease of the eye of the BVA. This prize is awarded by Bausch + Lomb on the annual DOG Congress (www.dog.org). Dr. HadrianContinue reading

Events

The research unit FOR 2240 hosts a number of different formal events, including regular internal meetings of all principle investigators, invited guest lectures, visiting professors, retreats, and a symposium to be held near the end of the initial funding period.

Links

The research unit FOR 2240 is embedded in various institutional contexts and has close cooperative ties to various other projects and networks.