Three thematic areas

lymphatic vessels

Lymphatic vessels are an important part of the “afferent” arm of inflammatory and immune responses. Via lymphatic vessels, antigen-presenting cells and antigens from the periphery enter the regional lymph nodes to induce local immune responses.

microglia

Microglia-mediated retinal immune processes are an early occurring pathophysiological hallmark of hereditary retinal dystrophies, age-related macular degeneration, diabetic retinopathy and glaucoma.

macrophages

Macrophages along with resident microglial cells of the retina appear to play a key role in all ocular inflammatory processes to be studied here. Thus, certain polarized phenotypes of macrophages mesh intimately with pathological lymphangiogenesis.

Background and specific aims

Background

The eye is the most important human sensory organ with which we perceive 90 percent of all information in our environment. The optical transparency as well as a structural and functional integrity of the eye is essential for good vision.

Specific aims

The general goal of the FOR 2240 is the concerted investigation of the so far still poorly understood pathogenesis of aberrant immune processes of the eye and the development of innovative new diagnostic and therapeutic concepts.

News

Young Cologne Eye Researcher Dr. Karina Hadrian wins Prize of the DOG

The department of ophthalmology at the University Hospital of Cologne is very proud to announce that Dr. Karina Hadrian won the Sicca advancement award for research of the dry eye and surface disease of the eye of the BVA. This prize is awarded by Bausch + Lomb on the annual DOG Congress (www.dog.org). Dr. HadrianContinue reading

Elsevier Announces Most Cited Ophthalmology Articles

Consensus Definition for Atrophy Associated with Age-Related Macular Degeneration on OCT: Classification of Atrophy Report 3 is one of the most quoted papers according to the Elsevier Most Cited Ophthalmology Articles overview https://bit.ly/3224En0 As part of the Classification of Atrophy Meetings (CAM) program, Prof. Dr. Sandra Liakopoulos of the Department of Ophthalmology at the UniversityContinue reading

New study identifies a novel role for TSPO in immune-related eye disease providing new treatment options for age-related macular degeneration (AMD)

In a cooperative approach the team around Thomas Langmann (Laboratory of the Exp. Immunology of the Eye at the Center for Ophthalmology and the CMMC) together with the team of Michael Schramm (Inst. of Med. Microbiology, Immunology and Hygiene) at the Univ. Hospital of Cologne and the Univ. of Cologne has identified a new mechanismContinue reading

Events

The research unit FOR 2240 hosts a number of different formal events, including regular internal meetings of all principle investigators, invited guest lectures, visiting professors, retreats, and a symposium to be held near the end of the initial funding period.

Links

The research unit FOR 2240 is embedded in various institutional contexts and has close cooperative ties to various other projects and networks.