Three thematic areas

lymphatic vessels

Lymphatic vessels are an important part of the “afferent” arm of inflammatory and immune responses. Via lymphatic vessels, antigen-presenting cells and antigens from the periphery enter the regional lymph nodes to induce local immune responses.

microglia

Microglia-mediated retinal immune processes are an early occurring pathophysiological hallmark of hereditary retinal dystrophies, age-related macular degeneration, diabetic retinopathy and glaucoma.

macrophages

Macrophages along with resident microglial cells of the retina appear to play a key role in all ocular inflammatory processes to be studied here. Thus, certain polarized phenotypes of macrophages mesh intimately with pathological lymphangiogenesis.

Background and specific aims

Background

The eye is the most important human sensory organ with which we perceive 90 percent of all information in our environment. The optical transparency as well as a structural and functional integrity of the eye is essential for good vision.

Specific aims

The general goal of the FOR 2240 is the concerted investigation of the so far still poorly understood pathogenesis of aberrant immune processes of the eye and the development of innovative new diagnostic and therapeutic concepts.

News

NEW European Union COST ACTION on Aniridia co-chaired in Cologne

ANIRIDIA-NET(https://aniridia-net.eu/) is a pan-European bottom-up network of researchers, ophthalmologist, trainees, aniridia patient organizations, industry and special interest groups funded by the European Cooperation in Science and Technology (COST) program (link) to improve aniridia clinical management and promote innovative research and development of new alternatives for its diagnosis and treatment. The COST Action runs from 2019-2023Continue reading

Cologne eye researchers sweep up prizes in Berlin (again!)

An astounding number of awards for outstanding scientific achievements, eight in total, went to scientists and clinician-scientists of the Department of Ophthalmology at the University of Cologne and the DFG FOR2240 at the annual meeting of the German Ophthalmological Society (DOG) held in Berlin from September 26th to 29th 2019. Important parts of the prize-winningContinue reading

Double triumph for cologne scientist.

This year’s DOG Patent 2019 award went to Dr. Thomas Clahsen for his exceptional inventions in the area of ophthalmology. Dr. Clahsen is working at the University Hospital Cologne in the Department of Ophthalmology (Experimental Ophthalmology). This specific award is only given once a year and honors outstanding translational research and application for a patentContinue reading

Events

The research unit FOR 2240 hosts a number of different formal events, including regular internal meetings of all principle investigators, invited guest lectures, visiting professors, retreats, and a symposium to be held near the end of the initial funding period.

Links

The research unit FOR 2240 is embedded in various institutional contexts and has close cooperative ties to various other projects and networks.