Three thematic areas

lymphatic vessels

Lymphatic vessels are an important part of the “afferent” arm of inflammatory and immune responses. Via lymphatic vessels, antigen-presenting cells and antigens from the periphery enter the regional lymph nodes to induce local immune responses.

microglia

Microglia-mediated retinal immune processes are an early occurring pathophysiological hallmark of hereditary retinal dystrophies, age-related macular degeneration, diabetic retinopathy and glaucoma.

macrophages

Macrophages along with resident microglial cells of the retina appear to play a key role in all ocular inflammatory processes to be studied here. Thus, certain polarized phenotypes of macrophages mesh intimately with pathological lymphangiogenesis.

Background and specific aims

Background

The eye is the most important human sensory organ with which we perceive 90 percent of all information in our environment. The optical transparency as well as a structural and functional integrity of the eye is essential for good vision.

Specific aims

The general goal of the FOR 2240 is the concerted investigation of the so far still poorly understood pathogenesis of aberrant immune processes of the eye and the development of innovative new diagnostic and therapeutic concepts.

News

Pole position in Germany for the Department of Ophthalmology at University of Cologne

Number 1 in scientific publications and impact factor The demand for research within ophthalmology is and will be high. Today many conditions of the eye can be treated successfully – also thanks to intensive and continuing research. But there are still many research questions pending. And the pressure to actContinue reading

Young Cologne Eye Researcher Dr. Yanhong Hou wins the Science Prize of the Eye Foundation of the DOG

(“Wissenschaftspreis der Stiftung Auge der Deutschen Ophthalmologischen Gesellschaft”) In July 2019, Dr. Yanhong Hou was declared the winner of the Science Prize (“Wissenschaftspreis”) of the Eye Foundation (“Stiftung Auge”) of the German Ophthalmological Society (DOG). Dr. Hou will be awarded during a ceremony at the annual congress of DOG from the board members of theContinue reading

Visiting Professor from Harvard University is guest at FOR 2240 and CMMC in Cologne

On 21st of June 2019 Prof. Bruce Ksander visited the DFG Research Unit FOR 2240 and the Center for Molecular Medicine at University Hospital Cologne. Prof. Ksander is Associate Professor at the Department of Ophthalmology at Harvard Medical School and Co-director of the MEEI Oncology Center of Excellence. His teamContinue reading

Events

The research unit FOR 2240 hosts a number of different formal events, including regular internal meetings of all principle investigators, invited guest lectures, visiting professors, retreats, and a symposium to be held near the end of the initial funding period.

Links

The research unit FOR 2240 is embedded in various institutional contexts and has close cooperative ties to various other projects and networks.