Three thematic areas

lymphatic vessels

Lymphatic vessels are an important part of the “afferent” arm of inflammatory and immune responses. Via lymphatic vessels, antigen-presenting cells and antigens from the periphery enter the regional lymph nodes to induce local immune responses.

microglia

Microglia-mediated retinal immune processes are an early occurring pathophysiological hallmark of hereditary retinal dystrophies, age-related macular degeneration, diabetic retinopathy and glaucoma.

macrophages

Macrophages along with resident microglial cells of the retina appear to play a key role in all ocular inflammatory processes to be studied here. Thus, certain polarized phenotypes of macrophages mesh intimately with pathological lymphangiogenesis.

Background and specific aims

Background

The eye is the most important human sensory organ with which we perceive 90 percent of all information in our environment. The optical transparency as well as a structural and functional integrity of the eye is essential for good vision.

Specific aims

The general goal of the FOR 2240 is the concerted investigation of the so far still poorly understood pathogenesis of aberrant immune processes of the eye and the development of innovative new diagnostic and therapeutic concepts.

News

Two female FOR Scientists selected for Mentoring Programs of the Medical Faculty

We are proud to announce that Ms Dr. Simona Schlereth and Ms Dr. Andrea Hedergott were selected to attend the MhÄK Mentoring program of the Medical Faculty at the University of Cologne.  The program is implemented for female physicians who are qualifying as a professor and runs this year for the very first time. TheContinue reading

Aniridie – new project against blindness

Aniridie is a rare but very serious inherent eye disease which is difficult to treat. The iris of the affected is incomplete or has not been formed at all during pregnancy, additionally, patients often suffer from a vascularized, dull cornea. It is not seldom that patient has a deformity of their retina, both can causeContinue reading

Prof. Cursiefen re-elected to DFG Review Board

Professor Dr. Claus Cursiefen, Chairman of the Department of Ophthalmology of the University Hospital Cologne and Speaker of DFG FOR2240, has been re-elected to the DFG Review Board representing Ophthalmology . With him Professor Dr. Marius Ader from Regenerative Therapies Dresden, Technische Universität Dresden, Germany – CRTD Dresden received the most votes. Both have beenContinue reading

Events

The research unit FOR 2240 hosts a number of different formal events, including regular internal meetings of all principle investigators, invited guest lectures, visiting professors, retreats, and a symposium to be held near the end of the initial funding period.

Links

The research unit FOR 2240 is embedded in various institutional contexts and has close cooperative ties to various other projects and networks.